TY - JOUR
T1 - High-resolution 2D NMR spectra in inhomogeneous fields via 3D acquisition
AU - Lin, Yanqin
AU - Wei, Zhiliang
AU - Zhang, Liandi
AU - Lin, Liangjie
AU - Chen, Zhong
PY - 2014/4/18
Y1 - 2014/4/18
N2 - High-resolution nuclear magnetic resonance (NMR) spectroscopy plays an important role in chemical studies. Here, a pulse sequence, based on coherence transfer module of tracking differences of precession frequencies of two spins and spin echo module, is proposed to obtain two dimension (2D) high-resolution NMR spectra via 3D acquisition under large field inhomogeneity. The proposed scheme composes of simple hard pulses and rectangle gradients. Resulting 2D spectra exhibit chemical shift differences and J coupling splittings in two orthogonal dimensions. The method developed here may offer a promising way for in situ high-resolution NMR studies on combinatorial chemistry.
AB - High-resolution nuclear magnetic resonance (NMR) spectroscopy plays an important role in chemical studies. Here, a pulse sequence, based on coherence transfer module of tracking differences of precession frequencies of two spins and spin echo module, is proposed to obtain two dimension (2D) high-resolution NMR spectra via 3D acquisition under large field inhomogeneity. The proposed scheme composes of simple hard pulses and rectangle gradients. Resulting 2D spectra exhibit chemical shift differences and J coupling splittings in two orthogonal dimensions. The method developed here may offer a promising way for in situ high-resolution NMR studies on combinatorial chemistry.
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U2 - 10.1016/j.cplett.2014.03.019
DO - 10.1016/j.cplett.2014.03.019
M3 - Article
AN - SCOPUS:84897411486
SN - 0009-2614
VL - 599
SP - 44
EP - 50
JO - Chemical Physics Letters
JF - Chemical Physics Letters
ER -