High prevalence of hepatitis C in Egyptian patients with chronic liver disease

I. A. Waked, S. M. Saleh, M. S. Moustafa, A. A. Raouf, D. L. Thomas, G. T. Strickland

Research output: Contribution to journalArticlepeer-review

Abstract

The highest prevalence rates of hepatitis C virus infection in the world have been recently reported among Egyptian blood donors and frequent recipients of transfusions and other blood products. This is the first report, however, demonstrating hepatitis C as the most frequent association with chronic liver disease in Egypt. Of 1023 patients referred to the Liver Institute in Menoufia governorate for evaluation of chronic liver disease, 752 (73.5%) had antibodies to hepatitis C compared with 168 (16.4%) with hepatitis B surface antigen. Hepatitis C antibody was more common in patients with active schistosomiasis and patients without hepatitis B surface antigenaemia. Of 100 patients having liver biopsies, histological findings consistent with chronic viral hepatitis or its complications were found in 89 and antibody to hepatitis C was present in 75 (84.3%) of these patients with chronic hepatitis, active cirrhosis or hepatocellular carcinoma. These data pointing to the importance of hepatitis C as a cause of chronic liver disease in Egypt emphasise the necessity of studies delineating its routes of transmission in this country.

Original languageEnglish (US)
Pages (from-to)105-107
Number of pages3
JournalGut
Volume37
Issue number1
DOIs
StatePublished - Jul 1995

Keywords

  • Chronic hepatitis
  • Chronic liver disease
  • Cirrhosis
  • Epidemiology
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular carcinoma
  • Schistosomiasis

ASJC Scopus subject areas

  • Gastroenterology

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