Abstract
Extranasal colonization is increasingly recognized as an important reservoir for Staphylococcus aureus among high-risk populations. We conducted a cross-sectional study of multiple body site colonization among 173 randomly selected STD clinic patients in Baltimore, Maryland. Staphylococcal carriage at extranasal sites, including the oropharynx, groin, rectum, and genitals, was common among study subjects. The USA300 clone was particularly associated with multiple sites of colonization compared with non-USA300 strains (p = 01). Given their high burden of multi-site colonization and confluence of established staphylococcal risk factors, STD clinic patients may represent a community-based reservoir for S. aureus and be well suited for innovative infection control initiatives.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1040-1043 |
| Number of pages | 4 |
| Journal | Microbes and Infection |
| Volume | 14 |
| Issue number | 12 |
| DOIs | |
| State | Published - Oct 2012 |
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Keywords
- Community-associated MRSA
- Molecular epidemiology
- S. aureus
ASJC Scopus subject areas
- Microbiology
- Immunology
- Infectious Diseases
Cite this
High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients : An unrecognized reservoir. / Miko, Benjamin A.; Uhlemann, Anne Catrin; Gelman, Amanda; Lee, Caroline J.; Hafer, Cory A.; Sullivan, Sean B.; Shi, Qiuhu; Miller, Maureen; Zenilman, Jonathan Mark; Lowy, Franklin D.
In: Microbes and Infection, Vol. 14, No. 12, 10.2012, p. 1040-1043.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients
T2 - An unrecognized reservoir
AU - Miko, Benjamin A.
AU - Uhlemann, Anne Catrin
AU - Gelman, Amanda
AU - Lee, Caroline J.
AU - Hafer, Cory A.
AU - Sullivan, Sean B.
AU - Shi, Qiuhu
AU - Miller, Maureen
AU - Zenilman, Jonathan Mark
AU - Lowy, Franklin D.
PY - 2012/10
Y1 - 2012/10
N2 - Extranasal colonization is increasingly recognized as an important reservoir for Staphylococcus aureus among high-risk populations. We conducted a cross-sectional study of multiple body site colonization among 173 randomly selected STD clinic patients in Baltimore, Maryland. Staphylococcal carriage at extranasal sites, including the oropharynx, groin, rectum, and genitals, was common among study subjects. The USA300 clone was particularly associated with multiple sites of colonization compared with non-USA300 strains (p = 01). Given their high burden of multi-site colonization and confluence of established staphylococcal risk factors, STD clinic patients may represent a community-based reservoir for S. aureus and be well suited for innovative infection control initiatives.
AB - Extranasal colonization is increasingly recognized as an important reservoir for Staphylococcus aureus among high-risk populations. We conducted a cross-sectional study of multiple body site colonization among 173 randomly selected STD clinic patients in Baltimore, Maryland. Staphylococcal carriage at extranasal sites, including the oropharynx, groin, rectum, and genitals, was common among study subjects. The USA300 clone was particularly associated with multiple sites of colonization compared with non-USA300 strains (p = 01). Given their high burden of multi-site colonization and confluence of established staphylococcal risk factors, STD clinic patients may represent a community-based reservoir for S. aureus and be well suited for innovative infection control initiatives.
KW - Community-associated MRSA
KW - Molecular epidemiology
KW - S. aureus
UR - http://www.scopus.com/inward/record.url?scp=84866343434&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84866343434&partnerID=8YFLogxK
U2 - 10.1016/j.micinf.2012.06.004
DO - 10.1016/j.micinf.2012.06.004
M3 - Article
VL - 14
SP - 1040
EP - 1043
JO - Microbes and Infection
JF - Microbes and Infection
SN - 1286-4579
IS - 12
ER -