High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients: An unrecognized reservoir

Benjamin A. Miko; Anne Catrin Uhlemann; Amanda Gelman; Caroline J. Lee; Cory A. Hafer; Sean B. Sullivan; Qiuhu Shi; Maureen Miller; Jonathan Zenilman; Franklin D. Lowy

doi:10.1016/j.micinf.2012.06.004

High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients: An unrecognized reservoir

Benjamin A. Miko, Anne Catrin Uhlemann, Amanda Gelman, Caroline J. Lee, Cory A. Hafer, Sean B. Sullivan, Qiuhu Shi, Maureen Miller, Jonathan Zenilman, Franklin D. Lowy

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Extranasal colonization is increasingly recognized as an important reservoir for Staphylococcus aureus among high-risk populations. We conducted a cross-sectional study of multiple body site colonization among 173 randomly selected STD clinic patients in Baltimore, Maryland. Staphylococcal carriage at extranasal sites, including the oropharynx, groin, rectum, and genitals, was common among study subjects. The USA300 clone was particularly associated with multiple sites of colonization compared with non-USA300 strains (p = 01). Given their high burden of multi-site colonization and confluence of established staphylococcal risk factors, STD clinic patients may represent a community-based reservoir for S. aureus and be well suited for innovative infection control initiatives.

Original language	English (US)
Pages (from-to)	1040-1043
Number of pages	4
Journal	Microbes and Infection
Volume	14
Issue number	12
DOIs	https://doi.org/10.1016/j.micinf.2012.06.004
State	Published - Oct 2012

Keywords

Community-associated MRSA
Molecular epidemiology
S. aureus

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases

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10.1016/j.micinf.2012.06.004

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Miko, B. A., Uhlemann, A. C., Gelman, A., Lee, C. J., Hafer, C. A., Sullivan, S. B., Shi, Q., Miller, M., Zenilman, J., & Lowy, F. D. (2012). High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients: An unrecognized reservoir. Microbes and Infection, 14(12), 1040-1043. https://doi.org/10.1016/j.micinf.2012.06.004

High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients : An unrecognized reservoir. / Miko, Benjamin A.; Uhlemann, Anne Catrin; Gelman, Amanda; Lee, Caroline J.; Hafer, Cory A.; Sullivan, Sean B.; Shi, Qiuhu; Miller, Maureen; Zenilman, Jonathan; Lowy, Franklin D.

In: Microbes and Infection, Vol. 14, No. 12, 10.2012, p. 1040-1043.

Research output: Contribution to journal › Article › peer-review

Miko, BA, Uhlemann, AC, Gelman, A, Lee, CJ, Hafer, CA, Sullivan, SB, Shi, Q, Miller, M, Zenilman, J & Lowy, FD 2012, 'High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients: An unrecognized reservoir', Microbes and Infection, vol. 14, no. 12, pp. 1040-1043. https://doi.org/10.1016/j.micinf.2012.06.004

Miko, Benjamin A. ; Uhlemann, Anne Catrin ; Gelman, Amanda ; Lee, Caroline J. ; Hafer, Cory A. ; Sullivan, Sean B. ; Shi, Qiuhu ; Miller, Maureen ; Zenilman, Jonathan ; Lowy, Franklin D. / High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients : An unrecognized reservoir. In: Microbes and Infection. 2012 ; Vol. 14, No. 12. pp. 1040-1043.

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title = "High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients: An unrecognized reservoir",

abstract = "Extranasal colonization is increasingly recognized as an important reservoir for Staphylococcus aureus among high-risk populations. We conducted a cross-sectional study of multiple body site colonization among 173 randomly selected STD clinic patients in Baltimore, Maryland. Staphylococcal carriage at extranasal sites, including the oropharynx, groin, rectum, and genitals, was common among study subjects. The USA300 clone was particularly associated with multiple sites of colonization compared with non-USA300 strains (p = 01). Given their high burden of multi-site colonization and confluence of established staphylococcal risk factors, STD clinic patients may represent a community-based reservoir for S. aureus and be well suited for innovative infection control initiatives.",

keywords = "Community-associated MRSA, Molecular epidemiology, S. aureus",

author = "Miko, {Benjamin A.} and Uhlemann, {Anne Catrin} and Amanda Gelman and Lee, {Caroline J.} and Hafer, {Cory A.} and Sullivan, {Sean B.} and Qiuhu Shi and Maureen Miller and Jonathan Zenilman and Lowy, {Franklin D.}",

note = "Funding Information: This research was supported by Training in Interdisciplinary Research to Reduce Antimicrobial Resistance at Columbia University [NIH T90 NR010824].",

year = "2012",

month = oct,

doi = "10.1016/j.micinf.2012.06.004",

language = "English (US)",

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T2 - An unrecognized reservoir

AU - Miko, Benjamin A.

AU - Uhlemann, Anne Catrin

AU - Gelman, Amanda

AU - Lee, Caroline J.

AU - Hafer, Cory A.

AU - Sullivan, Sean B.

AU - Shi, Qiuhu

AU - Miller, Maureen

AU - Zenilman, Jonathan

AU - Lowy, Franklin D.

N1 - Funding Information: This research was supported by Training in Interdisciplinary Research to Reduce Antimicrobial Resistance at Columbia University [NIH T90 NR010824].

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AB - Extranasal colonization is increasingly recognized as an important reservoir for Staphylococcus aureus among high-risk populations. We conducted a cross-sectional study of multiple body site colonization among 173 randomly selected STD clinic patients in Baltimore, Maryland. Staphylococcal carriage at extranasal sites, including the oropharynx, groin, rectum, and genitals, was common among study subjects. The USA300 clone was particularly associated with multiple sites of colonization compared with non-USA300 strains (p = 01). Given their high burden of multi-site colonization and confluence of established staphylococcal risk factors, STD clinic patients may represent a community-based reservoir for S. aureus and be well suited for innovative infection control initiatives.

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KW - Molecular epidemiology

KW - S. aureus

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High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients: An unrecognized reservoir

Abstract

Keywords

ASJC Scopus subject areas

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