High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients

An unrecognized reservoir

Benjamin A. Miko, Anne Catrin Uhlemann, Amanda Gelman, Caroline J. Lee, Cory A. Hafer, Sean B. Sullivan, Qiuhu Shi, Maureen Miller, Jonathan Mark Zenilman, Franklin D. Lowy

Research output: Contribution to journalArticle

Abstract

Extranasal colonization is increasingly recognized as an important reservoir for Staphylococcus aureus among high-risk populations. We conducted a cross-sectional study of multiple body site colonization among 173 randomly selected STD clinic patients in Baltimore, Maryland. Staphylococcal carriage at extranasal sites, including the oropharynx, groin, rectum, and genitals, was common among study subjects. The USA300 clone was particularly associated with multiple sites of colonization compared with non-USA300 strains (p = 01). Given their high burden of multi-site colonization and confluence of established staphylococcal risk factors, STD clinic patients may represent a community-based reservoir for S. aureus and be well suited for innovative infection control initiatives.

Original languageEnglish (US)
Pages (from-to)1040-1043
Number of pages4
JournalMicrobes and Infection
Volume14
Issue number12
DOIs
StatePublished - Oct 2012

Fingerprint

Sexually Transmitted Diseases
Staphylococcus aureus
Clone Cells
Baltimore
Oropharynx
Groin
Infection Control
Rectum
Cross-Sectional Studies
Population

Keywords

  • Community-associated MRSA
  • Molecular epidemiology
  • S. aureus

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

Cite this

High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients : An unrecognized reservoir. / Miko, Benjamin A.; Uhlemann, Anne Catrin; Gelman, Amanda; Lee, Caroline J.; Hafer, Cory A.; Sullivan, Sean B.; Shi, Qiuhu; Miller, Maureen; Zenilman, Jonathan Mark; Lowy, Franklin D.

In: Microbes and Infection, Vol. 14, No. 12, 10.2012, p. 1040-1043.

Research output: Contribution to journalArticle

Miko, Benjamin A. ; Uhlemann, Anne Catrin ; Gelman, Amanda ; Lee, Caroline J. ; Hafer, Cory A. ; Sullivan, Sean B. ; Shi, Qiuhu ; Miller, Maureen ; Zenilman, Jonathan Mark ; Lowy, Franklin D. / High prevalence of colonization with Staphylococcus aureus clone USA300 at multiple body sites among sexually transmitted disease clinic patients : An unrecognized reservoir. In: Microbes and Infection. 2012 ; Vol. 14, No. 12. pp. 1040-1043.
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