TY - JOUR
T1 - High prevalence of alcohol use among hepatitis C virus antibody positive injection drug users in three US cities
AU - Campbell, Jennifer V.
AU - Hagan, Holly
AU - Latka, Mary H.
AU - Garfein, Richard S.
AU - Golub, Elizabeth T.
AU - Coady, Micaela H.
AU - Thomas, David L.
AU - Strathdee, Steffanie A.
N1 - Funding Information:
Financial support : Funding for this project was provided through a cooperative agreement from the National Institute on Drug Abuse (DA14499).
PY - 2006/2/28
Y1 - 2006/2/28
N2 - Injection drug users (IDUs) acquire the majority of new hepatitis C virus (HCV) infections and frequently use alcohol. Alcohol abuse accelerates liver disease among HCV-infected persons, can reduce the effectiveness of treatment for HCV infection and may be a contraindication for HCV treatment. HCV seropositive, HIV-negative IDUs aged 18-35 years in Baltimore, New York City and Seattle who were enrolled in a behavioral risk-reduction intervention trial underwent computerized self-interviews to assess baseline alcohol use and dependence and medical history. We measured problem alcohol use using the 10-item Alcohol Use Disorders Identification Test (AUDIT) scale. Of 598 participants, 84% responded "false" to: "it is safe for a person with HCV to drink alcohol". Problem drinking, defined as score ≥8 on AUDIT, was identified in 37%. Correlates of scoring ≥8 on AUDIT included homelessness, male gender, primarily injecting speedballs, having injected with used needles, prior alcohol treatment and depression. Although most HCV seropositive IDUs in our sample appear informed about their increased risk of liver disease from alcohol, two-fifths screened positive for problem alcohol use. These findings underscore the importance of referring HCV-positive persons to effective alcohol treatment programs to reduce future liver damage and improve eligibility for and effectiveness of treatment of HCV.
AB - Injection drug users (IDUs) acquire the majority of new hepatitis C virus (HCV) infections and frequently use alcohol. Alcohol abuse accelerates liver disease among HCV-infected persons, can reduce the effectiveness of treatment for HCV infection and may be a contraindication for HCV treatment. HCV seropositive, HIV-negative IDUs aged 18-35 years in Baltimore, New York City and Seattle who were enrolled in a behavioral risk-reduction intervention trial underwent computerized self-interviews to assess baseline alcohol use and dependence and medical history. We measured problem alcohol use using the 10-item Alcohol Use Disorders Identification Test (AUDIT) scale. Of 598 participants, 84% responded "false" to: "it is safe for a person with HCV to drink alcohol". Problem drinking, defined as score ≥8 on AUDIT, was identified in 37%. Correlates of scoring ≥8 on AUDIT included homelessness, male gender, primarily injecting speedballs, having injected with used needles, prior alcohol treatment and depression. Although most HCV seropositive IDUs in our sample appear informed about their increased risk of liver disease from alcohol, two-fifths screened positive for problem alcohol use. These findings underscore the importance of referring HCV-positive persons to effective alcohol treatment programs to reduce future liver damage and improve eligibility for and effectiveness of treatment of HCV.
KW - Alcohol
KW - Hepatitis C virus
KW - Injection drug users
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U2 - 10.1016/j.drugalcdep.2005.07.005
DO - 10.1016/j.drugalcdep.2005.07.005
M3 - Article
C2 - 16129567
AN - SCOPUS:31444441558
SN - 0376-8716
VL - 81
SP - 259
EP - 265
JO - Drug and alcohol dependence
JF - Drug and alcohol dependence
IS - 3
ER -