High-power thulium fiber laser ablation of the canine prostate

Nathaniel M. Fried, Keith E. Murray

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The Thulium fiber laser may have several advantages over current urology lasers, including smaller size, more efficient operation, improved spatial beam quality, more precise tissue incision, and operation in pulsed or continuous-wave modes. However, previous laser-tissue interaction studies utilizing the Thulium fiber laser have been limited to laser powers of less than 5 W. This study describes high-power Thulium fiber laser vaporization of the canine prostate, ex vivo. A continuous-wave, 110-watt Thulium fiber laser operating at a wavelength of 1.91 μm, delivered 88.5 ± 2.3 W of power through a 600-±m-core silica fiber for non-contact vaporization of canine prostates (n=6). The Thulium fiber laser vaporized prostate tissue at a rate of 0.83 ± 0.11 g/min. The thermal coagulation zone measured 500-2000 μm. The high-power Thulium fiber laser is capable of rapid vaporization and coagulation of the prostate, ex vivo. In vivo animal studies are currently in development for evaluation of the Thulium fiber laser for prostate vaporization and potential treatment of benign prostate hyperplasia.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
EditorsK.E. Bartels, L.S. Bass, W.T.W. Riese, K.W. Gregory, H. Hirschberg
Pages176-182
Number of pages7
Volume5686
DOIs
StatePublished - 2005
EventPhotonic Therapeutics and Diagnostics - San Jose, CA, United States
Duration: Jan 22 2005Jan 25 2005

Other

OtherPhotonic Therapeutics and Diagnostics
Country/TerritoryUnited States
CitySan Jose, CA
Period1/22/051/25/05

Keywords

  • Ablation
  • BPH
  • Fiber
  • Laser
  • Prostate
  • Thulium

ASJC Scopus subject areas

  • Engineering(all)

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