High-power laser vaporization of the canine prostate using a 110 W thulium fiber laser at 1.91 μm

Nathaniel M. Fried

Research output: Contribution to journalArticle

Abstract

Introduction: The Thulium fiber laser may have several advantages over current urology lasers, including smaller size, more efficient operation, improved spatial beam quality, more precise tissue incision, and operation in pulsed or continuous-wave modes. Previous laser-tissue interaction studies utilizing the Thulium fiber laser have been limited to laser powers of less than 5 W, restricting potential medical applications. This study describes the preliminary testing of a high-power Thulium fiber laser for vaporization of the canine prostate, ex vivo. Study Design/Materials and Methods: A continuous-wave, 110-W Thulium fiber laser operating at a wavelength of 1.91 μm, delivered 88.5 ± 2.3 W of power through a 600-μm-core silica fiber for non-contact vaporization of canine prostates (n = 6). Results: The Thulium fiber laser vaporized prostate tissue at a rate of 0.83 ± 0.11 g/minute. The thermal coagulation zone measured 500-2,000 μm, demonstrating the potential for hemostasis. Conclusions: The high-power Thulium fiber laser is capable of rapid vaporization and coagulation of the prostate. In vivo animal studies are currently being planned for evaluation of the Thulium fiber laser for potential treatment of benign prostate hyperplasia (BPH).

Original languageEnglish (US)
Pages (from-to)52-56
Number of pages5
JournalLasers in Surgery and Medicine
Volume36
Issue number1
DOIs
StatePublished - Jan 2005

Fingerprint

Thulium
Laser Therapy
Canidae
Prostate
Lasers
Volatilization
Urology
Hemostasis
Silicon Dioxide
Hyperplasia
Hot Temperature

Keywords

  • Ablation
  • BPH
  • Fiber
  • Laser
  • Prostate
  • Thulium
  • Vaporization

ASJC Scopus subject areas

  • Surgery

Cite this

High-power laser vaporization of the canine prostate using a 110 W thulium fiber laser at 1.91 μm. / Fried, Nathaniel M.

In: Lasers in Surgery and Medicine, Vol. 36, No. 1, 01.2005, p. 52-56.

Research output: Contribution to journalArticle

@article{780477bcda5547559af52d272b4a72c7,
title = "High-power laser vaporization of the canine prostate using a 110 W thulium fiber laser at 1.91 μm",
abstract = "Introduction: The Thulium fiber laser may have several advantages over current urology lasers, including smaller size, more efficient operation, improved spatial beam quality, more precise tissue incision, and operation in pulsed or continuous-wave modes. Previous laser-tissue interaction studies utilizing the Thulium fiber laser have been limited to laser powers of less than 5 W, restricting potential medical applications. This study describes the preliminary testing of a high-power Thulium fiber laser for vaporization of the canine prostate, ex vivo. Study Design/Materials and Methods: A continuous-wave, 110-W Thulium fiber laser operating at a wavelength of 1.91 μm, delivered 88.5 ± 2.3 W of power through a 600-μm-core silica fiber for non-contact vaporization of canine prostates (n = 6). Results: The Thulium fiber laser vaporized prostate tissue at a rate of 0.83 ± 0.11 g/minute. The thermal coagulation zone measured 500-2,000 μm, demonstrating the potential for hemostasis. Conclusions: The high-power Thulium fiber laser is capable of rapid vaporization and coagulation of the prostate. In vivo animal studies are currently being planned for evaluation of the Thulium fiber laser for potential treatment of benign prostate hyperplasia (BPH).",
keywords = "Ablation, BPH, Fiber, Laser, Prostate, Thulium, Vaporization",
author = "Fried, {Nathaniel M.}",
year = "2005",
month = "1",
doi = "10.1002/lsm.20126",
language = "English (US)",
volume = "36",
pages = "52--56",
journal = "Lasers in Surgery and Medicine",
issn = "0196-8092",
publisher = "Wiley-Liss Inc.",
number = "1",

}

TY - JOUR

T1 - High-power laser vaporization of the canine prostate using a 110 W thulium fiber laser at 1.91 μm

AU - Fried, Nathaniel M.

PY - 2005/1

Y1 - 2005/1

N2 - Introduction: The Thulium fiber laser may have several advantages over current urology lasers, including smaller size, more efficient operation, improved spatial beam quality, more precise tissue incision, and operation in pulsed or continuous-wave modes. Previous laser-tissue interaction studies utilizing the Thulium fiber laser have been limited to laser powers of less than 5 W, restricting potential medical applications. This study describes the preliminary testing of a high-power Thulium fiber laser for vaporization of the canine prostate, ex vivo. Study Design/Materials and Methods: A continuous-wave, 110-W Thulium fiber laser operating at a wavelength of 1.91 μm, delivered 88.5 ± 2.3 W of power through a 600-μm-core silica fiber for non-contact vaporization of canine prostates (n = 6). Results: The Thulium fiber laser vaporized prostate tissue at a rate of 0.83 ± 0.11 g/minute. The thermal coagulation zone measured 500-2,000 μm, demonstrating the potential for hemostasis. Conclusions: The high-power Thulium fiber laser is capable of rapid vaporization and coagulation of the prostate. In vivo animal studies are currently being planned for evaluation of the Thulium fiber laser for potential treatment of benign prostate hyperplasia (BPH).

AB - Introduction: The Thulium fiber laser may have several advantages over current urology lasers, including smaller size, more efficient operation, improved spatial beam quality, more precise tissue incision, and operation in pulsed or continuous-wave modes. Previous laser-tissue interaction studies utilizing the Thulium fiber laser have been limited to laser powers of less than 5 W, restricting potential medical applications. This study describes the preliminary testing of a high-power Thulium fiber laser for vaporization of the canine prostate, ex vivo. Study Design/Materials and Methods: A continuous-wave, 110-W Thulium fiber laser operating at a wavelength of 1.91 μm, delivered 88.5 ± 2.3 W of power through a 600-μm-core silica fiber for non-contact vaporization of canine prostates (n = 6). Results: The Thulium fiber laser vaporized prostate tissue at a rate of 0.83 ± 0.11 g/minute. The thermal coagulation zone measured 500-2,000 μm, demonstrating the potential for hemostasis. Conclusions: The high-power Thulium fiber laser is capable of rapid vaporization and coagulation of the prostate. In vivo animal studies are currently being planned for evaluation of the Thulium fiber laser for potential treatment of benign prostate hyperplasia (BPH).

KW - Ablation

KW - BPH

KW - Fiber

KW - Laser

KW - Prostate

KW - Thulium

KW - Vaporization

UR - http://www.scopus.com/inward/record.url?scp=13544267783&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13544267783&partnerID=8YFLogxK

U2 - 10.1002/lsm.20126

DO - 10.1002/lsm.20126

M3 - Article

C2 - 15662624

AN - SCOPUS:13544267783

VL - 36

SP - 52

EP - 56

JO - Lasers in Surgery and Medicine

JF - Lasers in Surgery and Medicine

SN - 0196-8092

IS - 1

ER -