Abstract
: Exposure of infants to antiretroviral drugs for prevention of mother-to-child transmission can induce resistance to nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs). Data from nine national surveys of pretreatment drug resistance in children newly diagnosed with HIV show high levels of resistance to NRTIs included in first-line antiretroviral treatment (ART) regimens (dual abacavir-lamivudine/emtricitabine resistance). Additional research is needed to determine the impact of NRTI resistance on treatment response and optimize infant ART.
Original language | English (US) |
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Pages (from-to) | 1567-1570 |
Number of pages | 4 |
Journal | AIDS (London, England) |
Volume | 34 |
Issue number | 10 |
DOIs | |
State | Published - Aug 1 2020 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Infectious Diseases