@article{e8954bec8eed4c51bcea8d32fb63055c,
title = "High levels of resistance to nucleoside/nucleotide reverse transcriptase inhibitors in newly diagnosed antiretroviral treatment-naive children in sub-Saharan Africa",
abstract = "Exposure of infants to antiretroviral drugs for prevention of mother-to-child transmission can induce resistance to nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs). Data from nine national surveys of pretreatment drug resistance in children newly diagnosed with HIV show high levels of resistance to NRTIs included in first-line antiretroviral treatment (ART) regimens (dual abacavir-lamivudine/emtricitabine resistance). Additional research is needed to determine the impact of NRTI resistance on treatment response and optimize infant ART.",
author = "Inzaule, {Seth C.} and Jordan, {Michael R.} and George Bello and Nellie Wadonda-Kabondo and Salou Mounerou and Mbulli, {Innocent A.} and Akanmu, {Sulaimon A.} and Adolfo Vubil and Gillian Hunt and Pontiano Kaleebu and Simangele Mthethwa-Hleza and Janet Dzangare and Patrick Njukeng and Martina Penazzato and {Rinke De Wit}, {Tobias F.} and Eshleman, {Susan H.} and Silvia Bertagnolio",
note = "Funding Information: Funding: Funding for these surveys was provided by the President's Emergency Plan for AIDS Relief through the Centers for Disease Control and Prevention, the Global Fund, Amsterdam Institute of Global Health and Development (AIGHD) and countries{\textquoteright} ministry of health. Publisher Copyright: {\textcopyright} 2020 Lippincott Williams and Wilkins. All rights reserved.",
year = "2020",
month = aug,
day = "1",
doi = "10.1097/QAD.0000000000002580",
language = "English (US)",
volume = "34",
pages = "1567--1570",
journal = "AIDS",
issn = "0269-9370",
publisher = "Lippincott Williams and Wilkins",
number = "10",
}