High-LET-emitting radionuclides for cancer therapy

George Sgouros

doi:10.1007/978-1-4020-8696-0_9

High-LET-emitting radionuclides for cancer therapy

George Sgouros

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

During the last 15 years, alpha-particle emitting radionuclides have been investigated as a possible new class of radionuclides for targeted therapy. Alpha-particles can deposit DNA damaging energy 100 to 1,000 times greater than beta-particles. In this chapter, the background and clinical experiences of targeted alpha-particle radioimmunotherapy use are discussed.

Original language	English (US)
Title of host publication	Targeted Radionuclide Tumor Therapy
Subtitle of host publication	Biological Aspects
Publisher	Springer Netherlands
Pages	175-180
Number of pages	6
ISBN (Print)	9781402086953
DOIs	https://doi.org/10.1007/978-1-4020-8696-0_9
State	Published - Dec 1 2008

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4020-8696-0_9

Cite this

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abstract = "During the last 15 years, alpha-particle emitting radionuclides have been investigated as a possible new class of radionuclides for targeted therapy. Alpha-particles can deposit DNA damaging energy 100 to 1,000 times greater than beta-particles. In this chapter, the background and clinical experiences of targeted alpha-particle radioimmunotherapy use are discussed.",

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AB - During the last 15 years, alpha-particle emitting radionuclides have been investigated as a possible new class of radionuclides for targeted therapy. Alpha-particles can deposit DNA damaging energy 100 to 1,000 times greater than beta-particles. In this chapter, the background and clinical experiences of targeted alpha-particle radioimmunotherapy use are discussed.

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High-LET-emitting radionuclides for cancer therapy

Abstract

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