High-LET-emitting radionuclides for cancer therapy

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

During the last 15 years, alpha-particle emitting radionuclides have been investigated as a possible new class of radionuclides for targeted therapy. Alpha-particles can deposit DNA damaging energy 100 to 1,000 times greater than beta-particles. In this chapter, the background and clinical experiences of targeted alpha-particle radioimmunotherapy use are discussed.

Original languageEnglish (US)
Title of host publicationTargeted Radionuclide Tumor Therapy
Subtitle of host publicationBiological Aspects
PublisherSpringer Netherlands
Pages175-180
Number of pages6
ISBN (Print)9781402086953
DOIs
StatePublished - Dec 1 2008

ASJC Scopus subject areas

  • Medicine(all)

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