High incidence of noninfectious esophagitis in orthotopic liver transplant (OLT) recipients.

Z. Karasu, S. Hulagu, A. Gurakar, A. Jazzar, B. Kerwin, E. Taydas, G. McMillon, A. Sebastian, H. Wright, B. Nour

Research output: Contribution to journalArticlepeer-review


Incidence of esophagitis among cirrhotics is similar to the general population; post-OLT course of this entity is not well known. The aim of this study was to assess the incidence of non-infectious esophagitis among OLT recipients. Patients with chronic liver disease who have been considered for transplantation have undergone esophagogastroduodenoscopy (EGD) for examination of the upper gastrointestinal tract. Following transplantation, some of these patients have required EGD for various reasons. EGD findings following transplantation were compared to that individual's pre-transplant findings. There were 173 patients and the median age was 49. The incidence of pre-transplant esophagitis was 7.5%, which increased to 22% after OLT (p > 0.0001). None had specific etiology. Etiology of this increase needs to be further investigated and the effects of immunosuppressive drugs on lower esophageal sprinter and gastric motility should be clarified. Use of acid suppressing drugs during the early post-transplant period should be considered.

Original languageEnglish (US)
Pages (from-to)43-45
Number of pages3
JournalThe Journal of the Oklahoma State Medical Association
Issue number2
StatePublished - Feb 2001
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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