High field localized proton spectroscopy in small volumes: Greatly improved localization and shimming using shielded strong gradients

Peter C Van Zijl, C. T W Moonen, J. R. Alger, J. S. Cohen, S. A. Chesnick

Research output: Contribution to journalArticle

Abstract

The availability of shielded gradients facilitates accurate single-voxel localized spectroscopy. Exact localization (90-99%) of volumes as small as 2 x 2 x 2 mm is demonstrated using a modified stimulated echo sequence. Strong gradient pulses (up to 200 mT/m) are employed to clear the stimulated echo of unwanted magnetization, enabling superior (single-scan) shimming of the selected volume. In vivo and in vitro proton NMR results at 4.7 T are presented.

Original languageEnglish (US)
Pages (from-to)256-265
Number of pages10
JournalMagnetic Resonance in Medicine
Volume10
Issue number2
StatePublished - 1989
Externally publishedYes

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Protons
Spectrum Analysis
In Vitro Techniques

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

High field localized proton spectroscopy in small volumes : Greatly improved localization and shimming using shielded strong gradients. / Van Zijl, Peter C; Moonen, C. T W; Alger, J. R.; Cohen, J. S.; Chesnick, S. A.

In: Magnetic Resonance in Medicine, Vol. 10, No. 2, 1989, p. 256-265.

Research output: Contribution to journalArticle

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