Abstract
High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 159-171 |
| Number of pages | 13 |
| Journal | Neuroimaging Clinics of North America |
| Volume | 22 |
| Issue number | 2 |
| DOIs | |
| State | Published - May 2012 |
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Keywords
- 7 Tesla
- High-resolution imaging
- MR angiography
- Neurodegenerative disease
- Spectroscopy
- Susceptibility-weighted imaging
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology
Cite this
High-Field Imaging of Neurodegenerative Diseases. / Versluis, M. J.; van der Grond, J.; van Buchem, M. A.; Van Zijl, Peter C; Webb, A. G.
In: Neuroimaging Clinics of North America, Vol. 22, No. 2, 05.2012, p. 159-171.Research output: Contribution to journal › Article
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TY - JOUR
T1 - High-Field Imaging of Neurodegenerative Diseases
AU - Versluis, M. J.
AU - van der Grond, J.
AU - van Buchem, M. A.
AU - Van Zijl, Peter C
AU - Webb, A. G.
PY - 2012/5
Y1 - 2012/5
N2 - High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.
AB - High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.
KW - 7 Tesla
KW - High-resolution imaging
KW - MR angiography
KW - Neurodegenerative disease
KW - Spectroscopy
KW - Susceptibility-weighted imaging
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U2 - 10.1016/j.nic.2012.02.005
DO - 10.1016/j.nic.2012.02.005
M3 - Article
C2 - 22548926
AN - SCOPUS:84860356453
VL - 22
SP - 159
EP - 171
JO - Neuroimaging Clinics of North America
JF - Neuroimaging Clinics of North America
SN - 1052-5149
IS - 2
ER -