High-Field Imaging of Neurodegenerative Diseases

M. J. Versluis, J. van der Grond, M. A. van Buchem, Peter C Van Zijl, A. G. Webb

Research output: Contribution to journalArticle

Abstract

High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.

Original languageEnglish (US)
Pages (from-to)159-171
Number of pages13
JournalNeuroimaging Clinics of North America
Volume22
Issue number2
DOIs
StatePublished - May 2012

Fingerprint

Neurodegenerative Diseases
Magnetic Resonance Imaging
Magnetic Resonance Angiography
Huntington Disease
Signal-To-Noise Ratio
Multiple Sclerosis
Spectrum Analysis
Alzheimer Disease
Iron
Research

Keywords

  • 7 Tesla
  • High-resolution imaging
  • MR angiography
  • Neurodegenerative disease
  • Spectroscopy
  • Susceptibility-weighted imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

Cite this

Versluis, M. J., van der Grond, J., van Buchem, M. A., Van Zijl, P. C., & Webb, A. G. (2012). High-Field Imaging of Neurodegenerative Diseases. Neuroimaging Clinics of North America, 22(2), 159-171. https://doi.org/10.1016/j.nic.2012.02.005

High-Field Imaging of Neurodegenerative Diseases. / Versluis, M. J.; van der Grond, J.; van Buchem, M. A.; Van Zijl, Peter C; Webb, A. G.

In: Neuroimaging Clinics of North America, Vol. 22, No. 2, 05.2012, p. 159-171.

Research output: Contribution to journalArticle

Versluis, MJ, van der Grond, J, van Buchem, MA, Van Zijl, PC & Webb, AG 2012, 'High-Field Imaging of Neurodegenerative Diseases', Neuroimaging Clinics of North America, vol. 22, no. 2, pp. 159-171. https://doi.org/10.1016/j.nic.2012.02.005
Versluis, M. J. ; van der Grond, J. ; van Buchem, M. A. ; Van Zijl, Peter C ; Webb, A. G. / High-Field Imaging of Neurodegenerative Diseases. In: Neuroimaging Clinics of North America. 2012 ; Vol. 22, No. 2. pp. 159-171.
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