High-Field Imaging of Neurodegenerative Diseases

M. J. Versluis; J. van der Grond; M. A. van Buchem; P. van Zijl; A. G. Webb

doi:10.1016/j.nic.2012.02.005

High-Field Imaging of Neurodegenerative Diseases

M. J. Versluis, J. van der Grond, M. A. van Buchem, P. van Zijl, A. G. Webb

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.

Original language	English (US)
Pages (from-to)	159-171
Number of pages	13
Journal	Neuroimaging Clinics of North America
Volume	22
Issue number	2
DOIs	https://doi.org/10.1016/j.nic.2012.02.005
State	Published - May 1 2012

Keywords

7 Tesla
High-resolution imaging
MR angiography
Neurodegenerative disease
Spectroscopy
Susceptibility-weighted imaging

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology

Access to Document

10.1016/j.nic.2012.02.005

Fingerprint Dive into the research topics of 'High-Field Imaging of Neurodegenerative Diseases'. Together they form a unique fingerprint.

Cite this

@article{b10b592d7b6f42e09785c1b20647d634,

title = "High-Field Imaging of Neurodegenerative Diseases",

abstract = "High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.",

keywords = "7 Tesla, High-resolution imaging, MR angiography, Neurodegenerative disease, Spectroscopy, Susceptibility-weighted imaging",

author = "Versluis, {M. J.} and {van der Grond}, J. and {van Buchem}, {M. A.} and {van Zijl}, P. and Webb, {A. G.}",

year = "2012",

month = may,

day = "1",

doi = "10.1016/j.nic.2012.02.005",

language = "English (US)",

volume = "22",

pages = "159--171",

journal = "Neuroimaging Clinics of North America",

issn = "1052-5149",

publisher = "W.B. Saunders Ltd",

number = "2",

}

TY - JOUR

T1 - High-Field Imaging of Neurodegenerative Diseases

AU - Versluis, M. J.

AU - van der Grond, J.

AU - van Buchem, M. A.

AU - van Zijl, P.

AU - Webb, A. G.

PY - 2012/5/1

Y1 - 2012/5/1

N2 - High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.

AB - High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.

KW - 7 Tesla

KW - High-resolution imaging

KW - MR angiography

KW - Neurodegenerative disease

KW - Spectroscopy

KW - Susceptibility-weighted imaging

UR - http://www.scopus.com/inward/record.url?scp=84860356453&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84860356453&partnerID=8YFLogxK

U2 - 10.1016/j.nic.2012.02.005

DO - 10.1016/j.nic.2012.02.005

M3 - Review article

C2 - 22548926

AN - SCOPUS:84860356453

VL - 22

SP - 159

EP - 171

JO - Neuroimaging Clinics of North America

JF - Neuroimaging Clinics of North America

SN - 1052-5149

IS - 2

ER -