Hiding in plain sight: A closer look at posterior cortical atrophy

Shin C. Beh, Brinda Muthusamy, Peter Calabresi, John Hart, David Zee, Vivek Patel, Elliot Frohman

Research output: Contribution to journalArticle

Abstract

Posterior cortical atrophy (PCA) is a neurodegenerative syndrome dominated by deterioration of higher visual function (particularly visuospatial and visuoperceptual abilities). It is most commonly due to Alzheimer’s disease pathology, but may also be caused by dementia with Lewy bodies, corticobasal degeneration or Creutzfeldt-Jakob disease. Patients often present to optometrists, ophthalmologists and/or neurologists with nonspecific visual complaints, and unless clinicians seek the specific symptoms and signs of PCA (beyond that of the ‘standard’ neurological examination), this infrequent disorder is easily missed, delaying its diagnosis and treatment. We review the clinical features of PCA, focusing on its visual manifestations, to help neurologists recognise this important syndrome.

Original languageEnglish (US)
Pages (from-to)5-13
Number of pages9
JournalPractical Neurology
Volume15
Issue number1
DOIs
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Clinical Neurology

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