TY - JOUR
T1 - Hidden Concepts in the History and Philosophy of Origins-of-Life Studies
T2 - a Workshop Report
AU - Mariscal, Carlos
AU - Barahona, Ana
AU - Aubert-Kato, Nathanael
AU - Aydinoglu, Arsev Umur
AU - Bartlett, Stuart
AU - Cárdenas, María Luz
AU - Chandru, Kuhan
AU - Cleland, Carol
AU - Cocanougher, Benjamin T.
AU - Comfort, Nathaniel
AU - Cornish-Bowden, Athel
AU - Deacon, Terrence
AU - Froese, Tom
AU - Giovannelli, Donato
AU - Hernlund, John
AU - Hut, Piet
AU - Kimura, Jun
AU - Maurel, Marie Christine
AU - Merino, Nancy
AU - Moreno, Alvaro
AU - Nakagawa, Mayuko
AU - Peretó, Juli
AU - Virgo, Nathaniel
AU - Witkowski, Olaf
AU - James Cleaves, H.
N1 - Publisher Copyright:
© 2019, Springer Nature B.V.
PY - 2019/9/1
Y1 - 2019/9/1
N2 - In this review, we describe some of the central philosophical issues facing origins-of-life research and provide a targeted history of the developments that have led to the multidisciplinary field of origins-of-life studies. We outline these issues and developments to guide researchers and students from all fields. With respect to philosophy, we provide brief summaries of debates with respect to (1) definitions (or theories) of life, what life is and how research should be conducted in the absence of an accepted theory of life, (2) the distinctions between synthetic, historical, and universal projects in origins-of-life studies, issues with strategies for inferring the origins of life, such as (3) the nature of the first living entities (the “bottom up” approach) and (4) how to infer the nature of the last universal common ancestor (the “top down” approach), and (5) the status of origins of life as a science. Each of these debates influences the others. Although there are clusters of researchers that agree on some answers to these issues, each of these debates is still open. With respect to history, we outline several independent paths that have led to some of the approaches now prevalent in origins-of-life studies. These include one path from early views of life through the scientific revolutions brought about by Linnaeus (von Linn.), Wöhler, Miller, and others. In this approach, new theories, tools, and evidence guide new thoughts about the nature of life and its origin. We also describe another family of paths motivated by a” circularity” approach to life, which is guided by such thinkers as Maturana & Varela, Gánti, Rosen, and others. These views echo ideas developed by Kant and Aristotle, though they do so using modern science in ways that produce exciting avenues of investigation. By exploring the history of these ideas, we can see how many of the issues that currently interest us have been guided by the contexts in which the ideas were developed. The disciplinary backgrounds of each of these scholars has influenced the questions they sought to answer, the experiments they envisioned, and the kinds of data they collected. We conclude by encouraging scientists and scholars in the humanities and social sciences to explore ways in which they can interact to provide a deeper understanding of the conceptual assumptions, structure, and history of origins-of-life research. This may be useful to help frame future research agendas and bring awareness to the multifaceted issues facing this challenging scientific question.
AB - In this review, we describe some of the central philosophical issues facing origins-of-life research and provide a targeted history of the developments that have led to the multidisciplinary field of origins-of-life studies. We outline these issues and developments to guide researchers and students from all fields. With respect to philosophy, we provide brief summaries of debates with respect to (1) definitions (or theories) of life, what life is and how research should be conducted in the absence of an accepted theory of life, (2) the distinctions between synthetic, historical, and universal projects in origins-of-life studies, issues with strategies for inferring the origins of life, such as (3) the nature of the first living entities (the “bottom up” approach) and (4) how to infer the nature of the last universal common ancestor (the “top down” approach), and (5) the status of origins of life as a science. Each of these debates influences the others. Although there are clusters of researchers that agree on some answers to these issues, each of these debates is still open. With respect to history, we outline several independent paths that have led to some of the approaches now prevalent in origins-of-life studies. These include one path from early views of life through the scientific revolutions brought about by Linnaeus (von Linn.), Wöhler, Miller, and others. In this approach, new theories, tools, and evidence guide new thoughts about the nature of life and its origin. We also describe another family of paths motivated by a” circularity” approach to life, which is guided by such thinkers as Maturana & Varela, Gánti, Rosen, and others. These views echo ideas developed by Kant and Aristotle, though they do so using modern science in ways that produce exciting avenues of investigation. By exploring the history of these ideas, we can see how many of the issues that currently interest us have been guided by the contexts in which the ideas were developed. The disciplinary backgrounds of each of these scholars has influenced the questions they sought to answer, the experiments they envisioned, and the kinds of data they collected. We conclude by encouraging scientists and scholars in the humanities and social sciences to explore ways in which they can interact to provide a deeper understanding of the conceptual assumptions, structure, and history of origins-of-life research. This may be useful to help frame future research agendas and bring awareness to the multifaceted issues facing this challenging scientific question.
KW - Artificial life
KW - Epistemology
KW - LUCA
KW - Multidisciplinary science
KW - Prebiotic evolution
KW - Self-organization
KW - Theories of life
UR - http://www.scopus.com/inward/record.url?scp=85071171523&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85071171523&partnerID=8YFLogxK
U2 - 10.1007/s11084-019-09580-x
DO - 10.1007/s11084-019-09580-x
M3 - Review article
C2 - 31399826
AN - SCOPUS:85071171523
SN - 0169-6149
VL - 49
SP - 111
EP - 145
JO - Origins of Life and Evolution of Biospheres
JF - Origins of Life and Evolution of Biospheres
IS - 3
ER -