Heterogeneous pulmonary phenotypes associated with mutations in the thyroid transcription factor gene NKX2-1

Medicine & Life Sciences

• Thyroid Gland 100%
• Transcription Factors 90%
• Phenotype 72%
• Mutation 67%
• Lung 64%
• Genes 48%
• Newborn Respiratory Distress Syndrome 37%
• Nervous System Malformations 34%
• Surface-Active Agents 28%
• Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress 27%
• Surfactant Dysfunction 23%
• Thyroid Nuclear Factor 1 19%
• Frameshift Mutation 16%
• Nonsense Codon 15%
• Interstitial Lung Diseases 14%
• Gene Deletion 14%
• Missense Mutation 13%
• Hypothyroidism 13%
• Neurologic Manifestations 13%
• Respiratory Tract Infections 12%
• Lung Diseases 12%
• Child 11%
• Electrons 10%
• Newborn Infant 10%
• Homeostasis 9%
• Growth 6%
• Proteins 4%