Abstract
In normal dogs, SPECT 99mTc Sestamibi (MIBI) and 201Tl myocardial perfusion images reconstructed with filtered backprojection (FBP) show a large decrease of counts in the septal wall (S) compared to the lateral wall (L). We evaluated the iterative method of Chang at 0 and 1 iterations (Chang0 and Chang1), and the Maximum Likelihood-Expectation Maximization with attenuation compensation (ML-EM-ATN) algorithm on data acquired from 5 normal dogs and from simulated projection data using a homogeneous count-density model of a normal canine myocardium in the attenuation field measured in one dog. Mean counts in the S and L regions were calculated from maximum-count circumferential profile arrays. The table shows mean ± s.d. S/L count ratios. Our results demonstrate that ML-EM-ATN and Chang1 result in improved uniformity, as measured by the S/L ratio.
Original language | English (US) |
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Pages (from-to) | 1290-1296 |
Number of pages | 7 |
Journal | IEEE Transactions on Nuclear Science |
Volume | 42 |
Issue number | 4 |
DOIs | |
State | Published - Aug 1995 |
Externally published | Yes |
ASJC Scopus subject areas
- Nuclear and High Energy Physics
- Nuclear Energy and Engineering
- Electrical and Electronic Engineering