Herrick’s 1910 Case Report of Sickle Cell Anemia: The Rest of the Story

Todd L. Savitt, Morton F. Goldberg

Research output: Contribution to journalArticlepeer-review


James B. Herrick’s 1910 article presenting the case of an anemic West Indian student with peculiar-shaped red blood cells was the first description of sickle cell anemia in Western medical literature. However, he told only part of the story. Records in Chicago, Washington, DC, and Grenada, West Indies, reveal more information about the events surrounding Herrick’s discovery and help put them in historical perspective. Herrick’s intern, Ernest E. Irons, abreast of the latest developments in medicine, actually performed the blood work and alerted Herrick about the odd-looking cells. Changing patterns in American race relations allowed the patient, Walter Clement Noel, to study dentistry in Chicago. He continued to receive care from Irons for 2 1/2 years, then returned to Grenada to practice dentistry. Noel died nine years after his return to Grenada, at age 32.

Original languageEnglish (US)
Pages (from-to)266-271
Number of pages6
JournalJAMA: The Journal of the American Medical Association
Issue number2
StatePublished - Jan 13 1989
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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