Herpesvirus regulation of selective autophagy

Mai Tram Vo, Young Bong Choi

Research output: Contribution to journalReview articlepeer-review

Abstract

Selective autophagy has emerged as a key mechanism of quality and quantity control responsible for the autophagic degradation of specific subcellular organelles and materials. In addition, a specific type of selective autophagy (xenophagy) is also activated as a line of defense against invading intracellular pathogens, such as viruses. However, viruses have evolved strategies to counteract the host’s antiviral defense and even to activate some proviral types of selective autophagy, such as mitophagy, for their successful infection and replication. This review discusses the current knowledge on the regulation of selective autophagy by human herpesviruses.

Original languageEnglish (US)
Article number820
JournalViruses
Volume13
Issue number5
DOIs
StatePublished - May 2021

Keywords

  • Aggrephagy
  • Autophagy
  • Ferritinophagy
  • Herpesviruses
  • Mitophagy
  • Nucleophagy
  • Selective autophagy
  • Virophagy

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology

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