Herpes zoster vasculitis presenting as giant cell arteritis with bilateral internuclear ophthalmoplegia

Nael A. Al-Abdulla, Vivian Rismondo, John S. Minkowski, Neil R. Miller

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: To present a case of herpes zoster vasculitis presenting as giant cell arteritis. DESIGN: Interventional case report. METHODS: A 77-year-old woman presented with sudden onset of diplopia associated with temple headaches and a previous history of herpes zoster ophthalmicus. A temporal artery biopsy was obtained and in-situ hybridization performed for herpes zoster DNA. RESULTS: The patient presented with a bilateral internuclear ophthalmoplegia. Initial diagnostic evaluation, including erythrocyte sedimentation rate, C-reactive protein, and temporal artery biopsy, was consistent with giant cell arteritis. However, in-situ hybridization of the temporal artery specimen was positive for herpes zoster DNA. CONCLUSIONS: Herpes zoster vasculitis may mimic giant cell arteritis and should be considered in the differential of any patient with presumed giant cell arteritis with suspicious findings, central nervous system involvement, or previous herpes zoster infection.

Original languageEnglish (US)
Pages (from-to)912-914
Number of pages3
JournalAmerican journal of ophthalmology
Volume134
Issue number6
DOIs
StatePublished - Dec 1 2002

ASJC Scopus subject areas

  • Ophthalmology

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