Herpes simplex and HIV infections and preterm PROM

Robert M. Ehsanipoor, Carol A. Major

Research output: Contribution to journalArticle

Abstract

Maternal human immunodeficiency virus (HIV) and genital herpes simplex virus (HSV) infection in pregnancy have potential for vertical transmission that may result in death or morbidity. The risk increases with preterm delivery and prolonged ruptured membranes. When managing preterm premature rupture of membranes, the risk of transmission must be weighed against the risk of prematurity. Before 32 to 34 weeks, expectant management is preferred for patients with well controlled HIV or recurrent active genital HSV infection. For patients with advanced HIV disease or primary genital HSV infection, the risk of vertical transmission is higher and many clinical factors need to be considered.

Original languageEnglish (US)
Pages (from-to)330-336
Number of pages7
JournalClinical Obstetrics and Gynecology
Volume54
Issue number2
DOIs
StatePublished - Jun 1 2011

Keywords

  • Human immunodeficiency virus
  • herpes simplex virus
  • preterm premature rupture of membranes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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