Abstract
Maternal human immunodeficiency virus (HIV) and genital herpes simplex virus (HSV) infection in pregnancy have potential for vertical transmission that may result in death or morbidity. The risk increases with preterm delivery and prolonged ruptured membranes. When managing preterm premature rupture of membranes, the risk of transmission must be weighed against the risk of prematurity. Before 32 to 34 weeks, expectant management is preferred for patients with well controlled HIV or recurrent active genital HSV infection. For patients with advanced HIV disease or primary genital HSV infection, the risk of vertical transmission is higher and many clinical factors need to be considered.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 330-336 |
| Number of pages | 7 |
| Journal | Clinical Obstetrics and Gynecology |
| Volume | 54 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 2011 |
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Keywords
- herpes simplex virus
- Human immunodeficiency virus
- preterm premature rupture of membranes
ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
Herpes simplex and HIV infections and preterm PROM. / Ehsanipoor, Robert M.; Major, Carol A.
In: Clinical Obstetrics and Gynecology, Vol. 54, No. 2, 06.2011, p. 330-336.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Herpes simplex and HIV infections and preterm PROM
AU - Ehsanipoor, Robert M.
AU - Major, Carol A.
PY - 2011/6
Y1 - 2011/6
N2 - Maternal human immunodeficiency virus (HIV) and genital herpes simplex virus (HSV) infection in pregnancy have potential for vertical transmission that may result in death or morbidity. The risk increases with preterm delivery and prolonged ruptured membranes. When managing preterm premature rupture of membranes, the risk of transmission must be weighed against the risk of prematurity. Before 32 to 34 weeks, expectant management is preferred for patients with well controlled HIV or recurrent active genital HSV infection. For patients with advanced HIV disease or primary genital HSV infection, the risk of vertical transmission is higher and many clinical factors need to be considered.
AB - Maternal human immunodeficiency virus (HIV) and genital herpes simplex virus (HSV) infection in pregnancy have potential for vertical transmission that may result in death or morbidity. The risk increases with preterm delivery and prolonged ruptured membranes. When managing preterm premature rupture of membranes, the risk of transmission must be weighed against the risk of prematurity. Before 32 to 34 weeks, expectant management is preferred for patients with well controlled HIV or recurrent active genital HSV infection. For patients with advanced HIV disease or primary genital HSV infection, the risk of vertical transmission is higher and many clinical factors need to be considered.
KW - herpes simplex virus
KW - Human immunodeficiency virus
KW - preterm premature rupture of membranes
UR - http://www.scopus.com/inward/record.url?scp=79955570937&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79955570937&partnerID=8YFLogxK
U2 - 10.1097/GRF.0b013e318217d7a6
DO - 10.1097/GRF.0b013e318217d7a6
M3 - Article
C2 - 21508703
AN - SCOPUS:79955570937
VL - 54
SP - 330
EP - 336
JO - Clinical Obstetrics and Gynecology
JF - Clinical Obstetrics and Gynecology
SN - 0009-9201
IS - 2
ER -