Abstract
A sample of 37 pairs of MZ and 26 pairs of like sex DZ twins, aged 15 yr and older, was studied. Horizontal cup/disc ratio was estimated clinically by stereoscopic examination of the nerve head as obtained using the Allen Thorpe contact lens at the Haag Streit biomicroscope. Twin zygosity was determined by blood serotyping. Differences between MZ and DZ samples with respect to intrapair variance and intraclass correlation coefficient were highly significant and were consistent with a major genetic influence on size of the normal physiologic cup. This finding of high heritability for measurements of cup diameter is in contrast to low heritability estimates found in a companion investigation on heritability of the effect of corticosteroids on intraocular pressure.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 32 |
| Number of pages | 1 |
| Journal | Acta Geneticae Medicae et Gemellologiae |
| Volume | 23 |
| Issue number | spec. nr. |
| State | Published - 1974 |
| Externally published | Yes |
ASJC Scopus subject areas
- Genetics(clinical)