HERG channel function: Beyond long QT

Joseph J. Babcock, Min Li

Research output: Contribution to journalReview articlepeer-review

Abstract

To date, research on the human ether-a-go-go related gene (hERG) has focused on this potassium channel's role in cardiac repolarization and Long QT Syndrome (LQTS). However, growing evidence implicates hERG in a diversity of physiologic and pathological processes. Here we discuss these other functions of hERG, particularly their impact on diseases beyond cardiac arrhythmia.

Original languageEnglish (US)
Pages (from-to)329-335
Number of pages7
JournalActa Pharmacologica Sinica
Volume34
Issue number3
DOIs
StatePublished - Mar 2013

Keywords

  • cancer
  • cardiotoxicity
  • hERG
  • long QT
  • potassium channel

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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