Heredofamilial Retinal Dystrophy in Guinea Baboons: I. A Histopathologic Study

Mark O.M. Tso, Rebecca M. Santos Anderson, Samuel J. Vainisi

Research output: Contribution to journalArticlepeer-review

Abstract

We performed a histopathologic study of a heredofamilial retinal dystrophy in a colony of Guinea baboons. A bull’s-eye appearance was noted in the maculas of six baboons of three generations. Histologic examination of 13 eyes from this colony showed primary degeneration of both rod and cone cells initially in the parafoveal region, which subsequently involved the photoreceptor cells of the equator and periphery of the retina. The retinal pigment epithelium and choriocapillaris showed mild changes in the early stages. This disease in baboons was compared with various human retinomaculopathies.

Original languageEnglish (US)
Pages (from-to)1597-1603
Number of pages7
JournalArchives of ophthalmology
Volume101
Issue number10
DOIs
StatePublished - Oct 1983
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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