Hereditary spinal muscular atrophy in Brittany Spaniels: Clinical manifestations

M. D. Lorenz, L. C. Cork, J. W. Griffin, R. J. Adams, D. L. Price

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


A progressive neurologic disease was identified in a family of closely related Brittany Spaniel dogs. The disease developed in dogs less than 1 year old and characteristically resulted in paraspinal and proximal pelvic limb muscular atrophy. Neurologic examination, electrodiagnostic testing, and histologic studies indicated that the disease results from motor horn cell degeneration. A colony of affected dogs was established, and breeding studies incriminated an inherited basis for the disease.

Original languageEnglish (US)
Pages (from-to)833-839
Number of pages7
JournalJournal of the American Veterinary Medical Association
Issue number8
StatePublished - Dec 1 1979

ASJC Scopus subject areas

  • veterinary(all)


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