Hereditary angioedema: modification of clinical manifestations with androgens

P. J. Davis, F. B. Davis, P. Charache

Research output: Contribution to journalArticle

Abstract

Hereditary angio-neurotic edema is an autosomal dominant trait of decreased levels or function of circulating and tissue C'1 esterase inhibitor. The clinical illness is characterized by disabling episodes of peripheral, oropharyngeal and gut wall edema. Long term fluoxymesterone treatment of 5 affected males (393 patient months) and oxymetholone treatment of 6 affected females (204 patient months) has significantly decreased the frequency of attacks of edema without substantive side effects.

Original languageEnglish (US)
Pages (from-to)283-287
Number of pages5
JournalBirth Defects: Original Article Series
Volume12
Issue number6
StatePublished - 1976

Fingerprint

Hereditary Angioedemas
Androgens
Edema
Fluoxymesterone
Complement C1s
Oxymetholone
Therapeutics

ASJC Scopus subject areas

  • Developmental Biology
  • Genetics(clinical)

Cite this

Hereditary angioedema : modification of clinical manifestations with androgens. / Davis, P. J.; Davis, F. B.; Charache, P.

In: Birth Defects: Original Article Series, Vol. 12, No. 6, 1976, p. 283-287.

Research output: Contribution to journalArticle

Davis, P. J. ; Davis, F. B. ; Charache, P. / Hereditary angioedema : modification of clinical manifestations with androgens. In: Birth Defects: Original Article Series. 1976 ; Vol. 12, No. 6. pp. 283-287.
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