Herbicide exposure, Vietnam service, and hypertension risk in army chemical corps veterans

Yasmin S. Cypel, Amii M. Kress, Stephanie M. Eber, Aaron I. Schneiderman, Victoria J. Davey

Research output: Contribution to journalArticle

Abstract

Objective: We examined hypertension risk in Army Chemical Corps (ACC) veterans who sprayed defoliant in Vietnam. Methods: We analyzed data from the 2013 health survey of 3086 ACC veterans and investigated the association between self-reported physician-diagnosed-hypertension (SRH) and herbicide-spray-history adjusting for Vietnam-service-status, rank, age, tobacco/alcohol use, race, and body mass index (BMI). Spray-history was verified against serum 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (n=636). SRH was confirmed by blood pressure (BP) measurement by trained medical technicians and medical record reviews. Results: Herbicidespray-history (ORadjusted[95%confidence interval {CI}]=1.74[1.44,2.11]) and Vietnam-service-status (ORadjusted=1.26[1.05,1.53]) were significantly associated with SRH. The association was highest when comparing Vietnam-service-sprayers to non-Vietnam-service-nonsprayers (ORadjusted=2.21[1.76,2.77]). Serum TCDD was highest for Vietnamservice-sprayers. Mean systolic BPs were significantly higher among veterans with SRH than those without (P≤0.001). Medical records and SRH overall agreement was 89%. Conclusion: Occupational herbicide exposure history and Vietnam-service-status were significantly associated with hypertension risk.

Original languageEnglish (US)
Pages (from-to)1127-1136
Number of pages10
JournalJournal of occupational and environmental medicine
Volume58
Issue number11
DOIs
StatePublished - Nov 28 2016
Externally publishedYes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Fingerprint Dive into the research topics of 'Herbicide exposure, Vietnam service, and hypertension risk in army chemical corps veterans'. Together they form a unique fingerprint.

  • Cite this