Hepatoblastoma and familial adenomatous polyposis

J. E. Garber, F. P. Li, J. E. Kingston, A. J. Krush, L. C. Strong, M. J. Finegold, L. Bertario, S. Bülow, A. Filippone, T. Gedde-dahl, H. J. Järvinen

Research output: Contribution to journalArticle

Abstract

Eleven children have been identified as having hepatoblastoma and a family history of adenomatous polyposis, and 14 additional instances of this association have been collected from the literature. Among the 11 survivors of hepatoblastoma in the combined series, adenomatous lesions have been sought in seven and detected in six patients at ages 7 to 25 years. Five of these patients also have congenital hypertrophy of the rential pigment epithelium, a marker for carriers of the polyposis gene. These findings strengthen the association between hepatoblastoma and familial adenomatous polyposis and have led to the establishment of the Hepatoblastoma-Adenomatous Polyposis Registry.

Original languageEnglish (US)
Pages (from-to)1626-1628
Number of pages3
JournalJournal of the National Cancer Institute
Volume80
Issue number20
DOIs
StatePublished - Dec 21 1988

Fingerprint

Hepatoblastoma
Adenomatous Polyposis Coli
Pigments
Genes
Hypertrophy
Gene
Series
Survivors
Registries
Epithelium
History
Children
Family
Registry

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Oncology
  • Cancer Research

Cite this

Garber, J. E., Li, F. P., Kingston, J. E., Krush, A. J., Strong, L. C., Finegold, M. J., ... Järvinen, H. J. (1988). Hepatoblastoma and familial adenomatous polyposis. Journal of the National Cancer Institute, 80(20), 1626-1628. https://doi.org/10.1093/jnci/80.20.1626

Hepatoblastoma and familial adenomatous polyposis. / Garber, J. E.; Li, F. P.; Kingston, J. E.; Krush, A. J.; Strong, L. C.; Finegold, M. J.; Bertario, L.; Bülow, S.; Filippone, A.; Gedde-dahl, T.; Järvinen, H. J.

In: Journal of the National Cancer Institute, Vol. 80, No. 20, 21.12.1988, p. 1626-1628.

Research output: Contribution to journalArticle

Garber, JE, Li, FP, Kingston, JE, Krush, AJ, Strong, LC, Finegold, MJ, Bertario, L, Bülow, S, Filippone, A, Gedde-dahl, T & Järvinen, HJ 1988, 'Hepatoblastoma and familial adenomatous polyposis', Journal of the National Cancer Institute, vol. 80, no. 20, pp. 1626-1628. https://doi.org/10.1093/jnci/80.20.1626
Garber JE, Li FP, Kingston JE, Krush AJ, Strong LC, Finegold MJ et al. Hepatoblastoma and familial adenomatous polyposis. Journal of the National Cancer Institute. 1988 Dec 21;80(20):1626-1628. https://doi.org/10.1093/jnci/80.20.1626
Garber, J. E. ; Li, F. P. ; Kingston, J. E. ; Krush, A. J. ; Strong, L. C. ; Finegold, M. J. ; Bertario, L. ; Bülow, S. ; Filippone, A. ; Gedde-dahl, T. ; Järvinen, H. J. / Hepatoblastoma and familial adenomatous polyposis. In: Journal of the National Cancer Institute. 1988 ; Vol. 80, No. 20. pp. 1626-1628.
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