Hepatitis D virus and liver transplantation: Indications and outcomes

Haris Muhammad, Aniqa Tehreem, Muhammad Baraa Hammami, Peng Sheng Ting, Ahmet Gurakar, Ramzan Idilman

Research output: Contribution to journalArticlepeer-review


Hepatitis D virus (HDV) is a dependent virus that relies on hepatitis B virus for its replication and transmission. Chronic hepatitis D is a severe form of viral hepatitis that can result in end stage liver disease. Currently, pegylated interferon alpha is the only approved therapy for chronic HDV infection and is associated with significant side effects. Liver transplantation (LT) is the only treatment option for patients with end-stage liver disease, hepatocellular carcinoma, or fulminant hepatitis due to coinfection with HDV. As LT for HDV and hepatitis B virus coinfection is uncommon in the United States, most data on the long-term impact of LT on HDV are from international centers. In this review, we discuss the indications and results of LT with treatment options in HDV patients.

Original languageEnglish (US)
Pages (from-to)291-299
Number of pages9
JournalWorld Journal of Hepatology
Issue number3
StatePublished - 2021


  • Hepatitis B immunoglobins
  • Hepatitis delta virus
  • Hepatocellular carcinoma
  • Liver transplant

ASJC Scopus subject areas

  • Hepatology


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