Hepatitis C virus quasi-species dynamics predict progression of fibrosis after liver transplantation

Juan I. Arenas, Juan F. Gallegos-Orozco, Tomasz Laskus, Jeff Wilkinson, Amer Khatib, Carlos Fasola, Debra Adair, Marek Radkowski, Karen V. Kibler, Marek Nowicki, David Douglas, James Williams, George Netto, David Mulligan, Goran Klintmalm, Jorge Rakela, Hugo E. Vargas

Research output: Contribution to journalArticle

Abstract

Background. The dynamics of hepatitis C virus (HCV) quasi species in the E2 region may correlate with the course of infection after orthotopic liver transplantation (OLT). Methods. Thirty-four patients who underwent transplantation for HCV-related cirrhosis were studied. Serum and liver samples were available before OLT and at 1 week, 4 months, and 1 year after OLT. Patients were divided into group 1 (Knodell/Ishak fibrosis stage [FS] at 1 year,

Original languageEnglish (US)
Pages (from-to)2037-2046
Number of pages10
JournalJournal of Infectious Diseases
Volume189
Issue number11
DOIs
StatePublished - Apr 1 2004
Externally publishedYes

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Hepacivirus
Liver Transplantation
Fibrosis
Transplantation
Liver
Infection
Serum

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Immunology

Cite this

Arenas, J. I., Gallegos-Orozco, J. F., Laskus, T., Wilkinson, J., Khatib, A., Fasola, C., ... Vargas, H. E. (2004). Hepatitis C virus quasi-species dynamics predict progression of fibrosis after liver transplantation. Journal of Infectious Diseases, 189(11), 2037-2046. https://doi.org/10.1086/386338

Hepatitis C virus quasi-species dynamics predict progression of fibrosis after liver transplantation. / Arenas, Juan I.; Gallegos-Orozco, Juan F.; Laskus, Tomasz; Wilkinson, Jeff; Khatib, Amer; Fasola, Carlos; Adair, Debra; Radkowski, Marek; Kibler, Karen V.; Nowicki, Marek; Douglas, David; Williams, James; Netto, George; Mulligan, David; Klintmalm, Goran; Rakela, Jorge; Vargas, Hugo E.

In: Journal of Infectious Diseases, Vol. 189, No. 11, 01.04.2004, p. 2037-2046.

Research output: Contribution to journalArticle

Arenas, JI, Gallegos-Orozco, JF, Laskus, T, Wilkinson, J, Khatib, A, Fasola, C, Adair, D, Radkowski, M, Kibler, KV, Nowicki, M, Douglas, D, Williams, J, Netto, G, Mulligan, D, Klintmalm, G, Rakela, J & Vargas, HE 2004, 'Hepatitis C virus quasi-species dynamics predict progression of fibrosis after liver transplantation', Journal of Infectious Diseases, vol. 189, no. 11, pp. 2037-2046. https://doi.org/10.1086/386338
Arenas JI, Gallegos-Orozco JF, Laskus T, Wilkinson J, Khatib A, Fasola C et al. Hepatitis C virus quasi-species dynamics predict progression of fibrosis after liver transplantation. Journal of Infectious Diseases. 2004 Apr 1;189(11):2037-2046. https://doi.org/10.1086/386338
Arenas, Juan I. ; Gallegos-Orozco, Juan F. ; Laskus, Tomasz ; Wilkinson, Jeff ; Khatib, Amer ; Fasola, Carlos ; Adair, Debra ; Radkowski, Marek ; Kibler, Karen V. ; Nowicki, Marek ; Douglas, David ; Williams, James ; Netto, George ; Mulligan, David ; Klintmalm, Goran ; Rakela, Jorge ; Vargas, Hugo E. / Hepatitis C virus quasi-species dynamics predict progression of fibrosis after liver transplantation. In: Journal of Infectious Diseases. 2004 ; Vol. 189, No. 11. pp. 2037-2046.
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