Although many aspects of the transmission of hepatitis C virus (HCV) have been clarified, some important issues remain controversial, and the conventional wisdom may be based more on opinion than data. HCV is clearly transmitted by percutaneous exposure to contaminated blood, uncommonly from a mother to her infant and between sexual partners, and rarely during the provision of medical care in developed nations. Improved behavioral research instruments are needed to further the understanding of the practices that actually transmit infection. In addition, large, prospective studies are necessary to characterize the frequency of transmission between sexual partners and the potential role of cesarian section in reducing HCV transmission to infants.
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