Hepatic tumors of vascular origin: imaging appearances

Eric C. Ehman, Michael S. Torbenson, Michael L. Wells, Brian T. Welch, Scott M. Thompson, Ishan Garg, Sudhakar K. Venkatesh

Research output: Contribution to journalArticle

Abstract

A number of benign and malignant neoplasms may arise from the vascular elements within the liver parenchyma. Lesions discussed in this article include angiosarcoma, epithelioid hemangioendothelioma, solitary fibrous tumor (hemangiopericytoma), infantile, and cavernous hemangiomas. Despite a common theme of vascular origin, the pathologic and imaging appearance of these entities can be heterogeneous. Angiosarcomas are bizarrely enhancing, highly aggressive tumors, which often present with metastatic disease. When solitary, epithelioid hemangioendothelioma lesions can exhibit a concentric ring or target appearance on contrast-enhanced CT and at MR and when numerous may be indistinguishable from angiosarcoma except for a more slowly advancing course. Primary solitary fibrous tumors of the liver are exceedingly rare solid masses and most often initially diagnosed on imaging as other entities such as cholangiocarcinoma. Infantile hemangiomas consist of benign proliferation of the vascular endothelium and in the absence of flow-related complications, are usually clinically silent, and may be detected incidentally as T1 hypointense, T2 hyperintense, centripetally enhancing lesions. Cavernous hemangiomas are extremely common hepatic lesions and when classic rarely offer a challenge in diagnosis, though atypical variants may mimic more serious diseases. The purpose of this review is to provide an overview of important vascular tumors of the liver in order to aid the radiologist in providing a broad differential diagnosis for focal liver lesions, and when classic, suggest specific uncommonly seen diagnoses in order to more accurately guide clinical management.

Original languageEnglish (US)
Pages (from-to)1-13
Number of pages13
JournalAbdominal Radiology
DOIs
StateAccepted/In press - Nov 20 2017
Externally publishedYes

Fingerprint

Blood Vessels
Hemangiosarcoma
Epithelioid Hemangioendothelioma
Solitary Fibrous Tumors
Liver
Cavernous Hemangioma
Neoplasms
Hemangiopericytoma
Cholangiocarcinoma
Vascular Endothelium
Hemangioma
Differential Diagnosis

Keywords

  • Angiogenic
  • Liver
  • Neoplasm
  • Tumor
  • Vascular

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

Cite this

Ehman, E. C., Torbenson, M. S., Wells, M. L., Welch, B. T., Thompson, S. M., Garg, I., & Venkatesh, S. K. (Accepted/In press). Hepatic tumors of vascular origin: imaging appearances. Abdominal Radiology, 1-13. https://doi.org/10.1007/s00261-017-1401-3

Hepatic tumors of vascular origin : imaging appearances. / Ehman, Eric C.; Torbenson, Michael S.; Wells, Michael L.; Welch, Brian T.; Thompson, Scott M.; Garg, Ishan; Venkatesh, Sudhakar K.

In: Abdominal Radiology, 20.11.2017, p. 1-13.

Research output: Contribution to journalArticle

Ehman, EC, Torbenson, MS, Wells, ML, Welch, BT, Thompson, SM, Garg, I & Venkatesh, SK 2017, 'Hepatic tumors of vascular origin: imaging appearances', Abdominal Radiology, pp. 1-13. https://doi.org/10.1007/s00261-017-1401-3
Ehman EC, Torbenson MS, Wells ML, Welch BT, Thompson SM, Garg I et al. Hepatic tumors of vascular origin: imaging appearances. Abdominal Radiology. 2017 Nov 20;1-13. https://doi.org/10.1007/s00261-017-1401-3
Ehman, Eric C. ; Torbenson, Michael S. ; Wells, Michael L. ; Welch, Brian T. ; Thompson, Scott M. ; Garg, Ishan ; Venkatesh, Sudhakar K. / Hepatic tumors of vascular origin : imaging appearances. In: Abdominal Radiology. 2017 ; pp. 1-13.
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