Hepatic cavitation - A marker of transient hepatocellular injury during biliary lithotripsy

Leslie E. Forer, William J. Davros, Joanne Goldberg, Firas Al Kawas, Brian S. Garra, Wendelin Hayes, Robert K. Zeman

Research output: Contribution to journalArticle

Abstract

Sonographically visible microbubbles attributable to cavitation effects have been observed in bile (within the gallbladder), in hepatic vessels, and within the liver of patients undergoing biliary lithotripsy. Cavitation effects are believed to contribute to stone fragmentation and possibly tissue injury during lithotripsy. To study the latter, the relationship between intraparenchymal hepatic cavitation and serum transaminase activity and clinical follow-up was analyzed in 81 patients undergoing 164 lithotripsy treatments. Seventy-one treatments (43%) resulted in sonographically evident microbubbles in the liver parenchyma during lithotripsy. A temporary, yet statistically significant (P

Original languageEnglish (US)
Pages (from-to)1510-1516
Number of pages7
JournalDigestive Diseases and Sciences
Volume37
Issue number10
DOIs
StatePublished - Oct 1992
Externally publishedYes

Fingerprint

Lithotripsy
Microbubbles
Liver
Wounds and Injuries
Transaminases
Gallbladder
Bile
Therapeutics
Serum

Keywords

  • calculi
  • cavitation effects
  • gallbladder
  • lithotripsy
  • liver injury

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Forer, L. E., Davros, W. J., Goldberg, J., Al Kawas, F., Garra, B. S., Hayes, W., & Zeman, R. K. (1992). Hepatic cavitation - A marker of transient hepatocellular injury during biliary lithotripsy. Digestive Diseases and Sciences, 37(10), 1510-1516. https://doi.org/10.1007/BF01296495

Hepatic cavitation - A marker of transient hepatocellular injury during biliary lithotripsy. / Forer, Leslie E.; Davros, William J.; Goldberg, Joanne; Al Kawas, Firas; Garra, Brian S.; Hayes, Wendelin; Zeman, Robert K.

In: Digestive Diseases and Sciences, Vol. 37, No. 10, 10.1992, p. 1510-1516.

Research output: Contribution to journalArticle

Forer, Leslie E. ; Davros, William J. ; Goldberg, Joanne ; Al Kawas, Firas ; Garra, Brian S. ; Hayes, Wendelin ; Zeman, Robert K. / Hepatic cavitation - A marker of transient hepatocellular injury during biliary lithotripsy. In: Digestive Diseases and Sciences. 1992 ; Vol. 37, No. 10. pp. 1510-1516.
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