Hemophagocytic Lymphohistiocytosis Secondary to T Cell/Histiocyte-rich Large B Cell Lymphoma in an Adolescent Male

Jonathan L. Metts, Sunita I. Park, Michael A. Briones, Frank G. Keller

Research output: Contribution to journalArticlepeer-review

Abstract

Hemophagocytic Lymphohistiocytosis (HLH) is a hyperinflammatory disorder that may be encountered as a primary or secondary phenomenon. HLH secondary to lymphoma has been described, more frequently in adults than in children. T-cell/Histiocyte-rich B-cell lymphoma (THRLBCL) is a large B-cell lymphoma that resides in a microenvironment of robust host immune response and has previously been associated with HLH in adults. Here, we describe the first case of HLH secondary to THRLBCL in an adolescent patient.

Original languageEnglish (US)
Pages (from-to)95-99
Number of pages5
JournalPediatric and Developmental Pathology
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2018
Externally publishedYes

Keywords

  • hematopathology
  • hemophagocytic lymphohistiocytosis
  • histiocytosis
  • lymphoma
  • oncology
  • pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

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