Hemodynamic responses in brain dead organ donor patients

R. C. Wetzel, N. Setzer, J. L. Stiff, M. C. Rogers

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


Because we have noticed dramatic hemodynamic responses in brain dead patients undergoing surgery for organ donation, we analyzed the anesthetic records of cadaver organ donors. Ten records contain complete data for heart rate, blood pressure, central venous pressure, and time of incision. Systolic pressure increased by a mean of 31 torr (P < 0.01), diastolic pressure by 16 torr (P < 0.02), and heart rate by 23 beats/min (P < 0.01) in response to surgical stimulation. These results demonstrate the occurrence of significant hemodynamic responses to surgical stimuli in patients who fulfill the criteria of brain death, responses that do not, however, invalidate the current criteria for the diagnosis of brain death.

Original languageEnglish (US)
Pages (from-to)125-128
Number of pages4
JournalAnesthesia and analgesia
Issue number2
StatePublished - Jan 1 1985

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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