Hematolymphoid lesions of the sinonasal tract

Genevieve M. Crane, Amy S. Duffield

Research output: Contribution to journalArticlepeer-review

Abstract

Various hematolymphoid lesions involve the sinonasal tract, including aggressive B, T, and NK-cell neoplasms; myeloid sarcoma; low-grade lymphomas; indolent T-lymphoblastic proliferations; and Rosai-Dorfman disease. Differentiating aggressive lymphomas from non-hematopoietic neoplasms such as poorly differentiated squamous cell carcinoma, olfactory neuroblastoma, or sinonasal undifferentiated carcinoma may pose diagnostic challenges. In addition, the necrosis, vascular damage, and inflammatory infiltrates that are associated with some hematolymphoid disorders can result in misdiagnosis as infectious, autoimmune, or inflammatory conditions. Here, we review hematolymphoid disorders involving the sinonasal tract including their key clinical and histopathologic features.

Original languageEnglish (US)
Pages (from-to)71-80
Number of pages10
JournalSeminars in Diagnostic Pathology
Volume33
Issue number2
DOIs
StatePublished - Mar 1 2016

Keywords

  • Adult T-cell leukemia/lymphoma
  • Diffuse large B-cell lymphoma
  • Extranodal NK/T-cell lymphoma
  • Rosai-Dorfman disease
  • Sinonasal tract

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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