Helicobacter pylori y cáncer gástrico.

Translated title of the contribution: Helicobacter pylori and gastric cancer

R. León-Barúa, S. Recavarren-Arce, R. Berendson, Robert H Gilman

Research output: Contribution to journalArticle

Abstract

A review is done on the evidence in favor of a link between Helicobacter pylori infection and gastric cancer of the intestinal type. In countries at high risk of gastric cancer, like Perú, Hp infection begins early in life and is highly frequent and persistent. When Hp colonizes the gastric mucosa, it causes active chronic gastritis. Initially, the gastritis is of the superficial type. With time, and probably as a result of the concurrent action of nutritional, epidemiologic and immunologic modulating factors, chronic superficial gastritis may give rise to a progressive gastric pathology that leads to gastric premalignant lesions (chronic atrophic gastritis, intestinal metaplasia and dysplasia of the gastric mucosa) and increases the predisposition to gastric cancer. The principal modulating factors are described. The epidemiology of gastric premalignant lesions in Perú is also described. Finally, a discussion is done on the effect that eradication of Hp infection might have on the prevalence of gastric cancer.

Original languageSpanish
JournalRevista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
Volume15 Suppl 1
StatePublished - 1995
Externally publishedYes

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Helicobacter pylori
Stomach Neoplasms
Gastritis
Stomach
Gastric Mucosa
Atrophic Gastritis
Metaplasia
Immunologic Factors
Helicobacter Infections
Infection
Epidemiology
Pathology

Cite this

Helicobacter pylori y cáncer gástrico. / León-Barúa, R.; Recavarren-Arce, S.; Berendson, R.; Gilman, Robert H.

In: Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú, Vol. 15 Suppl 1, 1995.

Research output: Contribution to journalArticle

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