Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality

T. Harris, M. Visser, L. Ferrucci, H. Resnick, R. Tracy, R. Wallace

Research output: Contribution to journalArticle

Abstract

Heavier BMI has been associated with higher C-reactive protein (CRP), a marker of inflammation. We investigated CRP and its primary regulatory cytokine, IL6, in relation to BMI fertile and mortality using data from the Iowa 65+ Rural Health Study on 485 healthy men and women who never smoked cigarettes (mean age=77.8, follow up=4.6 years). Heavier BMI was strongly associated with higher log-transformed plasma IL-6 (pg/ml) and CRP (mg/L) in age-adjusted models. (*P

Original languageEnglish (US)
JournalFASEB Journal
Volume12
Issue number5
StatePublished - Mar 20 1998
Externally publishedYes

Fingerprint

C-reactive protein
interleukin-6
C-Reactive Protein
Interleukin-6
Mortality
rural health
Rural Health
cigarettes
Tobacco Products
cytokines
inflammation
Health
Cytokines
Inflammation
Plasmas

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology

Cite this

Harris, T., Visser, M., Ferrucci, L., Resnick, H., Tracy, R., & Wallace, R. (1998). Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality. FASEB Journal, 12(5).

Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality. / Harris, T.; Visser, M.; Ferrucci, L.; Resnick, H.; Tracy, R.; Wallace, R.

In: FASEB Journal, Vol. 12, No. 5, 20.03.1998.

Research output: Contribution to journalArticle

Harris, T, Visser, M, Ferrucci, L, Resnick, H, Tracy, R & Wallace, R 1998, 'Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality', FASEB Journal, vol. 12, no. 5.
Harris T, Visser M, Ferrucci L, Resnick H, Tracy R, Wallace R. Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality. FASEB Journal. 1998 Mar 20;12(5).
Harris, T. ; Visser, M. ; Ferrucci, L. ; Resnick, H. ; Tracy, R. ; Wallace, R. / Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality. In: FASEB Journal. 1998 ; Vol. 12, No. 5.
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