Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality

T. Harris, M. Visser, L. Ferrucci, H. Resnick, R. Tracy, R. Wallace

Research output: Contribution to journalArticle

Abstract

Heavier BMI has been associated with higher C-reactive protein (CRP), a marker of inflammation. We investigated CRP and its primary regulatory cytokine, IL6, in relation to BMI fertile and mortality using data from the Iowa 65+ Rural Health Study on 485 healthy men and women who never smoked cigarettes (mean age=77.8, follow up=4.6 years). Heavier BMI was strongly associated with higher log-transformed plasma IL-6 (pg/ml) and CRP (mg/L) in age-adjusted models. (*P

Original languageEnglish (US)
JournalFASEB Journal
Volume12
Issue number5
StatePublished - Mar 20 1998
Externally publishedYes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology

Fingerprint Dive into the research topics of 'Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality'. Together they form a unique fingerprint.

  • Cite this

    Harris, T., Visser, M., Ferrucci, L., Resnick, H., Tracy, R., & Wallace, R. (1998). Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality. FASEB Journal, 12(5).