Healthy aging and preclinical dementia: The United States-Israel Longitudinal Database Project

Ara S. Khachaturian, Joab Chapman, Lindsay Farrer, Robert P. Friedland, Richard Ebstein, Iris Grossman, Talma Hendler, Bruce Hermann, Rivka Inzelberg, Sterling Johnson, Zaven S. Khachaturian, Irit Lichter-Shapira, Oksana Makeeva, Robin Mayrl, Eli Mizrahi, Allen D. Roses, Mark Sager, Shifra Fraifeld

Research output: Contribution to journalArticlepeer-review


This article proposes the establishment of a United States-Israel Longitudinal Database for Healthy Aging and Preclinical Dementia as a prototype model for the eventual creation of an international database. It is envisioned that such a comprehensive international database, as a shared research resource, will provide the foundation for a systems approach to solve the dual public health problems of: (1) Early detection of individuals at an elevated risk of developing Alzheimer's disease, and (2) Developing interventions to delay onset of, or prevent, chronic brain disorders later in life.

Original languageEnglish (US)
Pages (from-to)475-481
Number of pages7
JournalAlzheimer's and Dementia
Issue number6
StatePublished - Nov 2010
Externally publishedYes


  • Aging
  • Alzheimer's disease
  • Biomarkers
  • Clinical trials
  • Cross-cultural
  • Database
  • Dementia
  • Family history
  • Genetics
  • Healthy aging
  • Imaging
  • Incidence
  • International
  • Mild cognitive impairment (MCI)
  • Parkinson's disease;
  • Prevalence
  • Prevention
  • Registry

ASJC Scopus subject areas

  • Health Policy
  • Epidemiology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience
  • Developmental Neuroscience
  • Clinical Neurology

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