Healthy aging and preclinical dementia: The United States-Israel Longitudinal Database Project

Ara S. Khachaturian; Joab Chapman; Lindsay Farrer; Robert P. Friedland; Richard Ebstein; Iris Grossman; Talma Hendler; Bruce Hermann; Rivka Inzelberg; Sterling Johnson; Zaven S. Khachaturian; Irit Lichter-Shapira; Oksana Makeeva; Robin Mayrl; Eli Mizrahi; Allen D. Roses; Mark Sager; Shifra Fraifeld

doi:10.1016/j.jalz.2010.10.001

Healthy aging and preclinical dementia: The United States-Israel Longitudinal Database Project

Ara S. Khachaturian, Joab Chapman, Lindsay Farrer, Robert P. Friedland, Richard Ebstein, Iris Grossman, Talma Hendler, Bruce Hermann, Rivka Inzelberg, Sterling Johnson, Zaven S. Khachaturian, Irit Lichter-Shapira, Oksana Makeeva, Robin Mayrl, Eli Mizrahi, Allen D. Roses, Mark Sager, Shifra Fraifeld

Research output: Contribution to journal › Article › peer-review

Abstract

This article proposes the establishment of a United States-Israel Longitudinal Database for Healthy Aging and Preclinical Dementia as a prototype model for the eventual creation of an international database. It is envisioned that such a comprehensive international database, as a shared research resource, will provide the foundation for a systems approach to solve the dual public health problems of: (1) Early detection of individuals at an elevated risk of developing Alzheimer's disease, and (2) Developing interventions to delay onset of, or prevent, chronic brain disorders later in life.

Original language	English (US)
Pages (from-to)	475-481
Number of pages	7
Journal	Alzheimer's and Dementia
Volume	6
Issue number	6
DOIs	https://doi.org/10.1016/j.jalz.2010.10.001
State	Published - Nov 2010
Externally published	Yes

Keywords

Aging
Alzheimer's disease
Biomarkers
Clinical trials
Cross-cultural
Database
Dementia
Family history
Genetics
Healthy aging
Imaging
Incidence
International
Mild cognitive impairment (MCI)
Parkinson's disease;
Prevalence
Prevention
Registry

ASJC Scopus subject areas

Health Policy
Epidemiology
Geriatrics and Gerontology
Psychiatry and Mental health
Cellular and Molecular Neuroscience
Developmental Neuroscience
Clinical Neurology

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10.1016/j.jalz.2010.10.001

Cite this

Khachaturian, A. S., Chapman, J., Farrer, L., Friedland, R. P., Ebstein, R., Grossman, I., Hendler, T., Hermann, B., Inzelberg, R., Johnson, S., Khachaturian, Z. S., Lichter-Shapira, I., Makeeva, O., Mayrl, R., Mizrahi, E., Roses, A. D., Sager, M., & Fraifeld, S. (2010). Healthy aging and preclinical dementia: The United States-Israel Longitudinal Database Project. Alzheimer's and Dementia, 6(6), 475-481. https://doi.org/10.1016/j.jalz.2010.10.001

Khachaturian, AS, Chapman, J, Farrer, L, Friedland, RP, Ebstein, R, Grossman, I, Hendler, T, Hermann, B, Inzelberg, R, Johnson, S, Khachaturian, ZS, Lichter-Shapira, I, Makeeva, O, Mayrl, R, Mizrahi, E, Roses, AD, Sager, M & Fraifeld, S 2010, 'Healthy aging and preclinical dementia: The United States-Israel Longitudinal Database Project', Alzheimer's and Dementia, vol. 6, no. 6, pp. 475-481. https://doi.org/10.1016/j.jalz.2010.10.001

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abstract = "This article proposes the establishment of a United States-Israel Longitudinal Database for Healthy Aging and Preclinical Dementia as a prototype model for the eventual creation of an international database. It is envisioned that such a comprehensive international database, as a shared research resource, will provide the foundation for a systems approach to solve the dual public health problems of: (1) Early detection of individuals at an elevated risk of developing Alzheimer's disease, and (2) Developing interventions to delay onset of, or prevent, chronic brain disorders later in life.",

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doi = "10.1016/j.jalz.2010.10.001",

language = "English (US)",

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AU - Grossman, Iris

AU - Hendler, Talma

AU - Hermann, Bruce

AU - Inzelberg, Rivka

AU - Johnson, Sterling

AU - Khachaturian, Zaven S.

AU - Lichter-Shapira, Irit

AU - Makeeva, Oksana

AU - Mayrl, Robin

AU - Mizrahi, Eli

AU - Roses, Allen D.

AU - Sager, Mark

AU - Fraifeld, Shifra

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KW - Alzheimer's disease

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KW - Clinical trials

KW - Cross-cultural

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KW - Genetics

KW - Healthy aging

KW - Imaging

KW - Incidence

KW - International

KW - Mild cognitive impairment (MCI)

KW - Parkinson's disease;

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KW - Prevention

KW - Registry

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Healthy aging and preclinical dementia: The United States-Israel Longitudinal Database Project

Abstract

Keywords

ASJC Scopus subject areas

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