Health related quality of life and psychosocial correlates among HIV-infected adolescent and young adult women in the US

Katherine Andrinopoulos, Gretchen Clum, Debra A. Murphy, Gary Harper, Lori Perez, Jiahong Xu, Shayna Cunningham, Jonathan M. Ellen

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Abstract

In this study HIV health-related quality of life (HIV-HRQOL) is examined among 179 behaviorally infected adolescent and young adult women. Modifiable psychosocial variables including depression, stigma, social support, and illness acceptance, and the biological end-points of CD4 cell count and viral load were explored in relation to HIV-HRQOL. The three factors of the HIV-HRQOL measure include current life satisfaction, illness related anxiety and illness burden. Bivariate linear regression analysis demonstrated statistically significant associations for all psychosocial variables and HIV-HRQOL factors (p <.01), but not foriological end-points. In multivariate linear regression analysis significant associations remained between: depression (p =.006), illness acceptance (p <.001), social support (p =.001), and current life satisfaction, and depression (p =.012), illness acceptance (p =.015), and illness burden. A trend in association was noted for HIV stigma, with current life satisfaction and illness related anxiety but did not reach statistical significance (p =.097 and p =.109 respectively). Interventions that effectively decrease stigma and depression and increase social support and illness acceptance will likely improve the well-being and quality of life of HIV-infected adolescent women.

Original languageEnglish (US)
Pages (from-to)367-381
Number of pages15
JournalAIDS Education and Prevention
Volume23
Issue number4
DOIs
StatePublished - Aug 1 2011

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ASJC Scopus subject areas

  • Health(social science)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Andrinopoulos, K., Clum, G., Murphy, D. A., Harper, G., Perez, L., Xu, J., Cunningham, S., & Ellen, J. M. (2011). Health related quality of life and psychosocial correlates among HIV-infected adolescent and young adult women in the US. AIDS Education and Prevention, 23(4), 367-381. https://doi.org/10.1521/aeap.2011.23.4.367