Head to head: should the intraductal component of invasive prostate cancer be graded?

Murali Varma; Jonathan I. Epstein

doi:10.1111/his.14216

Head to head: should the intraductal component of invasive prostate cancer be graded?

Murali Varma, Jonathan I. Epstein

School of Medicine

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

The reporting of intraductal carcinoma of the prostate (IDCP) is controversial, with conflicting recommendations having recently been published by the International Society of Urological Pathology (ISUP) and the Genitourinary Pathology Society (GUPS). Both recommend that isolated (pure) IDCP should not be graded. However, the ISUP recommends incorporating the IDCP component of invasive prostate cancer in the Gleason score, whereas the GUPS recommends reporting IDCP as a comment, independently of the Gleason score. The arguments for and against incorporating the IDCP component of invasive prostate cancer in the Gleason score are discussed in detail.

Original language	English (US)
Pages (from-to)	231-239
Number of pages	9
Journal	Histopathology
Volume	78
Issue number	2
DOIs	https://doi.org/10.1111/his.14216
State	Published - Jan 2021

Keywords

Genitourinary Pathology Society
Gleason grading
International Society of Urological Pathologists
intraductal carcinoma
prostate

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

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10.1111/his.14216

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@article{e93387d608f34d25871e29395ef4f873,

title = "Head to head: should the intraductal component of invasive prostate cancer be graded?",

abstract = "The reporting of intraductal carcinoma of the prostate (IDCP) is controversial, with conflicting recommendations having recently been published by the International Society of Urological Pathology (ISUP) and the Genitourinary Pathology Society (GUPS). Both recommend that isolated (pure) IDCP should not be graded. However, the ISUP recommends incorporating the IDCP component of invasive prostate cancer in the Gleason score, whereas the GUPS recommends reporting IDCP as a comment, independently of the Gleason score. The arguments for and against incorporating the IDCP component of invasive prostate cancer in the Gleason score are discussed in detail.",

keywords = "Genitourinary Pathology Society, Gleason grading, International Society of Urological Pathologists, intraductal carcinoma, prostate",

author = "Murali Varma and Epstein, {Jonathan I.}",

note = "Publisher Copyright: {\textcopyright} 2020 The Authors. Histopathology published by John Wiley & Sons Ltd",

year = "2021",

month = jan,

doi = "10.1111/his.14216",

language = "English (US)",

volume = "78",

pages = "231--239",

journal = "Histopathology",

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T2 - should the intraductal component of invasive prostate cancer be graded?

AU - Varma, Murali

AU - Epstein, Jonathan I.

PY - 2021/1

Y1 - 2021/1

N2 - The reporting of intraductal carcinoma of the prostate (IDCP) is controversial, with conflicting recommendations having recently been published by the International Society of Urological Pathology (ISUP) and the Genitourinary Pathology Society (GUPS). Both recommend that isolated (pure) IDCP should not be graded. However, the ISUP recommends incorporating the IDCP component of invasive prostate cancer in the Gleason score, whereas the GUPS recommends reporting IDCP as a comment, independently of the Gleason score. The arguments for and against incorporating the IDCP component of invasive prostate cancer in the Gleason score are discussed in detail.

AB - The reporting of intraductal carcinoma of the prostate (IDCP) is controversial, with conflicting recommendations having recently been published by the International Society of Urological Pathology (ISUP) and the Genitourinary Pathology Society (GUPS). Both recommend that isolated (pure) IDCP should not be graded. However, the ISUP recommends incorporating the IDCP component of invasive prostate cancer in the Gleason score, whereas the GUPS recommends reporting IDCP as a comment, independently of the Gleason score. The arguments for and against incorporating the IDCP component of invasive prostate cancer in the Gleason score are discussed in detail.

KW - Genitourinary Pathology Society

KW - Gleason grading

KW - International Society of Urological Pathologists

KW - intraductal carcinoma

KW - prostate

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DO - 10.1111/his.14216

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SP - 231

EP - 239

JO - Histopathology

JF - Histopathology

IS - 2

ER -

Head to head: should the intraductal component of invasive prostate cancer be graded?

Abstract

Keywords

ASJC Scopus subject areas

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