Head and neck cancers: Clinical practice guidelines

Arlene A. Forastiere, Kian Ang, David Brizel, Bruce Earl Brockstein, Frank Dunphy, David W. Eisele, Helmuth Goepfert, Wesley L. Hicks, Merrill S. Kies, William M. Lydiatt, Ellie Maghami, Thomas McCaffrey, Bharat B. Mittal, David G. Pfister, Harlan A. Pinto, Marshall R. Posner, John A. Ridge, Sandeep Samant, David E. Schuller, Jatin P. ShahSharon Spencer, Andrew Trotti, Richard H. Wheeler, Gregory T. Wolf, Frank Worden, Bevan Yueh

Research output: Contribution to journalReview article


The NCCN Head and Neck Cancers guidelines address tumors arising in the lip, oral cavity, oropharynx, hypopharynx, glottic and supraglottic larynx, paranasal (ethmoid and maxillary) sinuses, nasopharynx, and salivary glands, as well as occult primary cancer. Approximately 39,250 new cases of oral cavity, pharyngeal, and laryngeal cancers will occur in 2005, which accounts for about 3% of new cancer cases in the United States. An estimated 11,090 deaths from head and neck (H&N) cancers will occur in 2005. Alcohol and tobacco abuse are common etiologic factors in cancers of the oral cavity, oropharynx, hypopharynx, and larynx. Moreover, because the entire aerodigestive tract epithelium may be exposed to these carcinogens, patients with H&N cancer are at risk for developing second primary neoplasms of the H&N, lung, and esophagus.

Original languageEnglish (US)
Pages (from-to)316-391
Number of pages76
JournalJNCCN Journal of the National Comprehensive Cancer Network
Issue number3
StatePublished - May 1 2005


  • Chemotherapy
  • Head and neck cancer
  • Hypopharynx
  • Larynx
  • Lip
  • NCCN Clinical Practice Guidelines
  • Oral cavity
  • Oropharynx
  • Radiotherapy
  • Salivary glands
  • Sinuses
  • Surgery carcinoma

ASJC Scopus subject areas

  • Oncology

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  • Cite this

    Forastiere, A. A., Ang, K., Brizel, D., Brockstein, B. E., Dunphy, F., Eisele, D. W., Goepfert, H., Hicks, W. L., Kies, M. S., Lydiatt, W. M., Maghami, E., McCaffrey, T., Mittal, B. B., Pfister, D. G., Pinto, H. A., Posner, M. R., Ridge, J. A., Samant, S., Schuller, D. E., ... Yueh, B. (2005). Head and neck cancers: Clinical practice guidelines. JNCCN Journal of the National Comprehensive Cancer Network, 3(3), 316-391.