Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative

Peipei Ping; Åsa B. Gustafsson; Don M. Bers; Lothar A. Blatter; Hua Cai; Arshad Jahangir; Daniel Kelly; Deborah Muoio; Brian O'Rourke; Peter Rabinovitch; Natalia Trayanova; Jennifer Van Eyk; James N. Weiss; Renee Wong; Lisa Schwartz Longacre

doi:10.1161/CIRCRESAHA.117.306693

Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative

Peipei Ping, Åsa B. Gustafsson, Don M. Bers, Lothar A. Blatter, Hua Cai, Arshad Jahangir, Daniel Kelly, Deborah Muoio, Brian O'Rourke, Peter Rabinovitch, Natalia Trayanova, Jennifer Van Eyk, James N. Weiss, Renee Wong, Lisa Schwartz Longacre

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Mitochondrial biology is the sum of diverse phenomena from molecular profiles to physiological functions. A mechanistic understanding of mitochondria in disease development, and hence the future prospect of clinical translations, relies on a systems-level integration of expertise from multiple fields of investigation. Upon the successful conclusion of a recent National Institutes of Health, National Heart, Lung, and Blood Institute initiative on integrative mitochondrial biology in cardiovascular diseases, we reflect on the accomplishments made possible by this unique interdisciplinary collaboration effort and exciting new fronts on the study of these remarkable organelles.

Original language	English (US)
Pages (from-to)	234-238
Number of pages	5
Journal	Circulation research
Volume	117
Issue number	3
DOIs	https://doi.org/10.1161/CIRCRESAHA.117.306693
State	Published - Jul 17 2015

Keywords

National Heart, Lung, and Blood Institute (U.S.)
cardiovascular disease
cell death
heart diseases
mitochondria

ASJC Scopus subject areas

Physiology
Cardiology and Cardiovascular Medicine

Access to Document

10.1161/CIRCRESAHA.117.306693

Cite this

Ping, P., Gustafsson, Å. B., Bers, D. M., Blatter, L. A., Cai, H., Jahangir, A., Kelly, D., Muoio, D., O'Rourke, B., Rabinovitch, P., Trayanova, N., Van Eyk, J., Weiss, J. N., Wong, R., & Longacre, L. S. (2015). Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative. Circulation research, 117(3), 234-238. https://doi.org/10.1161/CIRCRESAHA.117.306693

Ping, P, Gustafsson, ÅB, Bers, DM, Blatter, LA, Cai, H, Jahangir, A, Kelly, D, Muoio, D, O'Rourke, B, Rabinovitch, P, Trayanova, N, Van Eyk, J, Weiss, JN, Wong, R & Longacre, LS 2015, 'Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative', Circulation research, vol. 117, no. 3, pp. 234-238. https://doi.org/10.1161/CIRCRESAHA.117.306693

@article{b9b096f4e1bf47f9b8a2a7b3dcecd8ea,

title = "Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative",

abstract = "Mitochondrial biology is the sum of diverse phenomena from molecular profiles to physiological functions. A mechanistic understanding of mitochondria in disease development, and hence the future prospect of clinical translations, relies on a systems-level integration of expertise from multiple fields of investigation. Upon the successful conclusion of a recent National Institutes of Health, National Heart, Lung, and Blood Institute initiative on integrative mitochondrial biology in cardiovascular diseases, we reflect on the accomplishments made possible by this unique interdisciplinary collaboration effort and exciting new fronts on the study of these remarkable organelles.",

keywords = "National Heart, Lung, and Blood Institute (U.S.), cardiovascular disease, cell death, heart diseases, mitochondria",

author = "Peipei Ping and Gustafsson, {{\AA}sa B.} and Bers, {Don M.} and Blatter, {Lothar A.} and Hua Cai and Arshad Jahangir and Daniel Kelly and Deborah Muoio and Brian O'Rourke and Peter Rabinovitch and Natalia Trayanova and {Van Eyk}, Jennifer and Weiss, {James N.} and Renee Wong and Longacre, {Lisa Schwartz}",

note = "Publisher Copyright: {\textcopyright} 2015 American Heart Association, Inc.",

year = "2015",

month = jul,

day = "17",

doi = "10.1161/CIRCRESAHA.117.306693",

language = "English (US)",

volume = "117",

pages = "234--238",

journal = "Circulation research",

issn = "0009-7330",

publisher = "Lippincott Williams and Wilkins",

number = "3",

}

TY - JOUR

T1 - Harnessing the Power of Integrated Mitochondrial Biology and Physiology

T2 - A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative

AU - Ping, Peipei

AU - Gustafsson, Åsa B.

AU - Bers, Don M.

AU - Blatter, Lothar A.

AU - Cai, Hua

AU - Jahangir, Arshad

AU - Kelly, Daniel

AU - Muoio, Deborah

AU - O'Rourke, Brian

AU - Rabinovitch, Peter

AU - Trayanova, Natalia

AU - Van Eyk, Jennifer

AU - Weiss, James N.

AU - Wong, Renee

AU - Longacre, Lisa Schwartz

PY - 2015/7/17

Y1 - 2015/7/17

N2 - Mitochondrial biology is the sum of diverse phenomena from molecular profiles to physiological functions. A mechanistic understanding of mitochondria in disease development, and hence the future prospect of clinical translations, relies on a systems-level integration of expertise from multiple fields of investigation. Upon the successful conclusion of a recent National Institutes of Health, National Heart, Lung, and Blood Institute initiative on integrative mitochondrial biology in cardiovascular diseases, we reflect on the accomplishments made possible by this unique interdisciplinary collaboration effort and exciting new fronts on the study of these remarkable organelles.

AB - Mitochondrial biology is the sum of diverse phenomena from molecular profiles to physiological functions. A mechanistic understanding of mitochondria in disease development, and hence the future prospect of clinical translations, relies on a systems-level integration of expertise from multiple fields of investigation. Upon the successful conclusion of a recent National Institutes of Health, National Heart, Lung, and Blood Institute initiative on integrative mitochondrial biology in cardiovascular diseases, we reflect on the accomplishments made possible by this unique interdisciplinary collaboration effort and exciting new fronts on the study of these remarkable organelles.

KW - National Heart, Lung, and Blood Institute (U.S.)

KW - cardiovascular disease

KW - cell death

KW - heart diseases

KW - mitochondria

UR - http://www.scopus.com/inward/record.url?scp=84937550029&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84937550029&partnerID=8YFLogxK

U2 - 10.1161/CIRCRESAHA.117.306693

DO - 10.1161/CIRCRESAHA.117.306693

M3 - Article

C2 - 26185209

AN - SCOPUS:84937550029

SN - 0009-7330

VL - 117

SP - 234

EP - 238

JO - Circulation research

JF - Circulation research

IS - 3

ER -

Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this