Harmonization of detailed clinical models with clinical study data standards

Guoqian Jiang, Julie Evans, Tom Oniki, Joey Coyle, Landen Bain, Stan Huff, Rebecca Kush, Christopher G. Chute

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Data sharing and integration between clinical research data management system (CDMS) and electronic health record (EHR) system remains a challenging issue. To deal with the challenge, there is emerging interest in utilizing the Detailed Clinical Modeling (DCM) approach across a variety of contexts. The Intermountain Healthcare Clinical Element Models (CEMs) have been adopted by the Office of the National Coordinator (ONC) awarded SHARPn project for normalizing patient data from the electronic medical records (EMRs). The objective of the present study is to describe our preliminary efforts on harmonization of the SHARPn CEMs with CDISC (Clinical Data Interchange Standards Consortium) clinical study data standards. We were focused on three generic domains: Demographics, Lab Tests and Medications. We performed a panel review on each data element extracted from the CDISC templates and SHARPn CEMs. We have identified a set of data elements that are common to the context of both clinical research and secondary use and discussed outstanding harmonization issues. We consider that the outcomes would be useful for defining new requirements for the DCM modeling community and ultimately facilitating the semantic interoperability between systems for both clinical research and secondary use.

Original languageEnglish (US)
Title of host publicationMIX-HS'12 - Proceedings of the 2nd International Workshop on Managing Interoperability and Complexity in Health Systems, Co-located with CIKM 2012
Pages23-30
Number of pages8
DOIs
StatePublished - Dec 7 2012
Event2nd International Workshop on Managing Interoperability and Complexity in Health Systems, MIX-HS 2012, Collocated with the 21st ACM International Conference on Information and Knowledge Management, CIKM 2012 - Maui, HI, United States
Duration: Oct 29 2012Oct 29 2012

Publication series

NameInternational Conference on Information and Knowledge Management, Proceedings

Other

Other2nd International Workshop on Managing Interoperability and Complexity in Health Systems, MIX-HS 2012, Collocated with the 21st ACM International Conference on Information and Knowledge Management, CIKM 2012
CountryUnited States
CityMaui, HI
Period10/29/1210/29/12

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Keywords

  • Clinical research
  • Data standards
  • Detailed clinical models
  • Electronic medical records

ASJC Scopus subject areas

  • Decision Sciences(all)
  • Business, Management and Accounting(all)

Cite this

Jiang, G., Evans, J., Oniki, T., Coyle, J., Bain, L., Huff, S., Kush, R., & Chute, C. G. (2012). Harmonization of detailed clinical models with clinical study data standards. In MIX-HS'12 - Proceedings of the 2nd International Workshop on Managing Interoperability and Complexity in Health Systems, Co-located with CIKM 2012 (pp. 23-30). (International Conference on Information and Knowledge Management, Proceedings). https://doi.org/10.1145/2389672.2389678