Half-cone SPECT system for small animal imaging

Heng Li, Yibin Zheng, Alexander V. Stolin, Bijoy K. Kundu, Mark B. Williams

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Molecular imaging studies using small animals such as mice require the development of high-sensitivity, high-resolution pinhole SPECT imaging systems. It is well known that the photon detection efficiency drops remarkably as the pinhole angle increases, and spatial resolution decreases as the magnification factor decreases. To obtain high efficiency and high resolution, the pinhole should be put as close as possible to the object while the pinhole angle remains as small as possible. To address these conflicting requirements, we proposed a half-cone imaging geometry in which the detector looks at only half of the FOV in each view, while the FOV being reconstructed remain the same. Our preliminary results demonstrated that SPECT system using this geometry could achieve higher sensitivity and better spatial resolution.

Original languageEnglish (US)
Title of host publication2006 3rd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro - Proceedings
Pages1236-1239
Number of pages4
StatePublished - Nov 17 2006
Externally publishedYes
Event2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Arlington, VA, United States
Duration: Apr 6 2006Apr 9 2006

Publication series

Name2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings
Volume2006

Other

Other2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro
CountryUnited States
CityArlington, VA
Period4/6/064/9/06

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Li, H., Zheng, Y., Stolin, A. V., Kundu, B. K., & Williams, M. B. (2006). Half-cone SPECT system for small animal imaging. In 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings (pp. 1236-1239). [1625148] (2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings; Vol. 2006).