Abstract
DATA from lesion studies data indicate that the removal of the medial cerebellum prevents acquisition but not reten-tion of long-term habituation (LTH) of the acoustic startle response (ASR). The spreading depression (SD) of the vermis was used to examine under more functional conditions the build-up of LTH of the ASR in Wistar rats. Our findings showed that reversible blockade of the vermis during training disrupted LTH of the ASR without changing within-trials habituation. In contrast to previous data, the present results suggest that SD strongly affects the amplitude of the startle response. The data are discussed in respect to a role of the vermis in the control of emotional behaviour in animals.
Original language | English (US) |
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Pages (from-to) | 2065-2068 |
Number of pages | 4 |
Journal | Neuroreport |
Volume | 5 |
Issue number | 16 |
DOIs | |
State | Published - Oct 1994 |
Externally published | Yes |
Keywords
- Habituation
- Rats
- Spreading depression
- Startle
ASJC Scopus subject areas
- Neuroscience(all)