Gynecologic Malignancies

Gita Suneja, Akila Viswanathan

Research output: Contribution to journalReview article

Abstract

Gynecologic malignancies are among the most prevalent cancers affecting women worldwide, but they are heterogeneous diseases with varying risk factors, management paradigms, and outcomes. Gynecologic cancers mediated by human papillomavirus (HPV) are preventable and curable with early detection and treatment. Dramatic reductions in cervical cancer incidence and mortality have been achieved through cancer screening and HPV vaccination. Radiotherapy plays a central role in the management of gynecologic malignancies. For some cancers, radiotherapy alone can be curative. More often, radiotherapy is used in conjunction with surgery and systemic therapy to improve locoregional control and extend overall survival. This chapter reviews recent advances in radiotherapeutic management of gynecologic malignancies.

Original languageEnglish (US)
Pages (from-to)71-89
Number of pages19
JournalHematology/Oncology Clinics of North America
Volume34
Issue number1
DOIs
StatePublished - Feb 2020

Fingerprint

Neoplasms
Radiotherapy
Risk Management
Early Detection of Cancer
Uterine Cervical Neoplasms
Vaccination
Survival
Mortality
Incidence
Therapeutics

Keywords

  • Brachytherapy
  • Cervical cancer
  • Image guidance
  • Intensity modulated radiotherapy
  • Uterine cancer
  • Vulvar cancer

ASJC Scopus subject areas

  • Hematology
  • Oncology

Cite this

Gynecologic Malignancies. / Suneja, Gita; Viswanathan, Akila.

In: Hematology/Oncology Clinics of North America, Vol. 34, No. 1, 02.2020, p. 71-89.

Research output: Contribution to journalReview article

@article{4c8818e059c24f9ab314f3a03466684c,
title = "Gynecologic Malignancies",
abstract = "Gynecologic malignancies are among the most prevalent cancers affecting women worldwide, but they are heterogeneous diseases with varying risk factors, management paradigms, and outcomes. Gynecologic cancers mediated by human papillomavirus (HPV) are preventable and curable with early detection and treatment. Dramatic reductions in cervical cancer incidence and mortality have been achieved through cancer screening and HPV vaccination. Radiotherapy plays a central role in the management of gynecologic malignancies. For some cancers, radiotherapy alone can be curative. More often, radiotherapy is used in conjunction with surgery and systemic therapy to improve locoregional control and extend overall survival. This chapter reviews recent advances in radiotherapeutic management of gynecologic malignancies.",
keywords = "Brachytherapy, Cervical cancer, Image guidance, Intensity modulated radiotherapy, Uterine cancer, Vulvar cancer",
author = "Gita Suneja and Akila Viswanathan",
year = "2020",
month = "2",
doi = "10.1016/j.hoc.2019.08.018",
language = "English (US)",
volume = "34",
pages = "71--89",
journal = "Hematology/Oncology Clinics of North America",
issn = "0889-8588",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Gynecologic Malignancies

AU - Suneja, Gita

AU - Viswanathan, Akila

PY - 2020/2

Y1 - 2020/2

N2 - Gynecologic malignancies are among the most prevalent cancers affecting women worldwide, but they are heterogeneous diseases with varying risk factors, management paradigms, and outcomes. Gynecologic cancers mediated by human papillomavirus (HPV) are preventable and curable with early detection and treatment. Dramatic reductions in cervical cancer incidence and mortality have been achieved through cancer screening and HPV vaccination. Radiotherapy plays a central role in the management of gynecologic malignancies. For some cancers, radiotherapy alone can be curative. More often, radiotherapy is used in conjunction with surgery and systemic therapy to improve locoregional control and extend overall survival. This chapter reviews recent advances in radiotherapeutic management of gynecologic malignancies.

AB - Gynecologic malignancies are among the most prevalent cancers affecting women worldwide, but they are heterogeneous diseases with varying risk factors, management paradigms, and outcomes. Gynecologic cancers mediated by human papillomavirus (HPV) are preventable and curable with early detection and treatment. Dramatic reductions in cervical cancer incidence and mortality have been achieved through cancer screening and HPV vaccination. Radiotherapy plays a central role in the management of gynecologic malignancies. For some cancers, radiotherapy alone can be curative. More often, radiotherapy is used in conjunction with surgery and systemic therapy to improve locoregional control and extend overall survival. This chapter reviews recent advances in radiotherapeutic management of gynecologic malignancies.

KW - Brachytherapy

KW - Cervical cancer

KW - Image guidance

KW - Intensity modulated radiotherapy

KW - Uterine cancer

KW - Vulvar cancer

UR - http://www.scopus.com/inward/record.url?scp=85074939727&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85074939727&partnerID=8YFLogxK

U2 - 10.1016/j.hoc.2019.08.018

DO - 10.1016/j.hoc.2019.08.018

M3 - Review article

C2 - 31739953

AN - SCOPUS:85074939727

VL - 34

SP - 71

EP - 89

JO - Hematology/Oncology Clinics of North America

JF - Hematology/Oncology Clinics of North America

SN - 0889-8588

IS - 1

ER -