Gut peptides in the control of food intake: 30 Years of ideas

Research output: Contribution to journalArticle

Abstract

The demonstration of the ability of exogenous cholecystokinin (CCK) to inhibit food intake began a series of investigations into whether and how gut and brain peptides affected ingestive behavior. In that original demonstration, Gerry Smith and colleagues both established criteria for evaluating roles for gut peptides in food intake and shifted the focus of feeding controls to factors that contribute to limiting meal size. Although new gut peptides with novel mechanisms and durations of action have been identified in the past few years, Smith's criteria and his distinction between direct and indirect controls of meal size continue to provide a framework for understanding how such peptides may contribute to overall feeding control.

Original languageEnglish (US)
Pages (from-to)175-180
Number of pages6
JournalPhysiology and Behavior
Volume82
Issue number1
DOIs
StatePublished - Aug 2004

Fingerprint

Eating
Peptides
Meals
Cholecystokinin
Brain

Keywords

  • Cholecystokinin
  • Food intake
  • Gut peptides

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Physiology (medical)

Cite this

Gut peptides in the control of food intake : 30 Years of ideas. / Moran, Timothy H.

In: Physiology and Behavior, Vol. 82, No. 1, 08.2004, p. 175-180.

Research output: Contribution to journalArticle

@article{4172a8ed66624df2be3404602cf481ce,
title = "Gut peptides in the control of food intake: 30 Years of ideas",
abstract = "The demonstration of the ability of exogenous cholecystokinin (CCK) to inhibit food intake began a series of investigations into whether and how gut and brain peptides affected ingestive behavior. In that original demonstration, Gerry Smith and colleagues both established criteria for evaluating roles for gut peptides in food intake and shifted the focus of feeding controls to factors that contribute to limiting meal size. Although new gut peptides with novel mechanisms and durations of action have been identified in the past few years, Smith's criteria and his distinction between direct and indirect controls of meal size continue to provide a framework for understanding how such peptides may contribute to overall feeding control.",
keywords = "Cholecystokinin, Food intake, Gut peptides",
author = "Moran, {Timothy H}",
year = "2004",
month = "8",
doi = "10.1016/j.physbeh.2004.04.048",
language = "English (US)",
volume = "82",
pages = "175--180",
journal = "Physiology and Behavior",
issn = "0031-9384",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Gut peptides in the control of food intake

T2 - 30 Years of ideas

AU - Moran, Timothy H

PY - 2004/8

Y1 - 2004/8

N2 - The demonstration of the ability of exogenous cholecystokinin (CCK) to inhibit food intake began a series of investigations into whether and how gut and brain peptides affected ingestive behavior. In that original demonstration, Gerry Smith and colleagues both established criteria for evaluating roles for gut peptides in food intake and shifted the focus of feeding controls to factors that contribute to limiting meal size. Although new gut peptides with novel mechanisms and durations of action have been identified in the past few years, Smith's criteria and his distinction between direct and indirect controls of meal size continue to provide a framework for understanding how such peptides may contribute to overall feeding control.

AB - The demonstration of the ability of exogenous cholecystokinin (CCK) to inhibit food intake began a series of investigations into whether and how gut and brain peptides affected ingestive behavior. In that original demonstration, Gerry Smith and colleagues both established criteria for evaluating roles for gut peptides in food intake and shifted the focus of feeding controls to factors that contribute to limiting meal size. Although new gut peptides with novel mechanisms and durations of action have been identified in the past few years, Smith's criteria and his distinction between direct and indirect controls of meal size continue to provide a framework for understanding how such peptides may contribute to overall feeding control.

KW - Cholecystokinin

KW - Food intake

KW - Gut peptides

UR - http://www.scopus.com/inward/record.url?scp=3242742898&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3242742898&partnerID=8YFLogxK

U2 - 10.1016/j.physbeh.2004.04.048

DO - 10.1016/j.physbeh.2004.04.048

M3 - Article

C2 - 15234609

AN - SCOPUS:3242742898

VL - 82

SP - 175

EP - 180

JO - Physiology and Behavior

JF - Physiology and Behavior

SN - 0031-9384

IS - 1

ER -