Gut healing: Haemocytes aid via Sax and Tkv jazzes it down

Lesley N. Weaver, Daniela Drummond-Barbosa

Research output: Contribution to journalReview articlepeer-review

Abstract

Control of stem cell activity is essential for accurate regeneration. Pathogen- or chemical-induced intestinal damage is now shown to recruit haemocytes expressing bone morphogenetic protein signals that stimulate proliferation of intestinal stem cells and subsequently induce their quiescence, in conjunction with muscle-derived bone morphogenetic proteins. A temporal switch in expression of Type I receptors enables this two-phase response.

Original languageEnglish (US)
Pages (from-to)707-709
Number of pages3
JournalNature cell biology
Volume17
Issue number6
DOIs
StatePublished - Jun 1 2015

ASJC Scopus subject areas

  • Cell Biology

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