Abstract
Control of stem cell activity is essential for accurate regeneration. Pathogen- or chemical-induced intestinal damage is now shown to recruit haemocytes expressing bone morphogenetic protein signals that stimulate proliferation of intestinal stem cells and subsequently induce their quiescence, in conjunction with muscle-derived bone morphogenetic proteins. A temporal switch in expression of Type I receptors enables this two-phase response.
Original language | English (US) |
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Pages (from-to) | 707-709 |
Number of pages | 3 |
Journal | Nature cell biology |
Volume | 17 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2015 |
ASJC Scopus subject areas
- Cell Biology