Guidelines for the retention, storage, and use of residual dried blood spot samples after newborn screening analysis: Statement of the council of regional networks for genetic services

Bradford L. Therrell, W. Harry Hannon, Kenneth A. Pass, Fred Lorey, Charles Brokopp, James Eckman, Mike Glass, Randy Heidenreich, Shari Kinney, Sydney Kling, Gretchen Landenburger, F. John Meaney, Edward R B Mccabe, Susan R. Panny, Marion Schwartz, Emmanuel Shapira

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Abstract

These guidelines provide scientific information for policy development by state health departments considering appropriate use of newborn screening specimens after screening tests are finished. Information was collected, debated, and formulated into a policy statement by the Newborn Screening Committee of the Council of Regional Networks for Genetic Services (CORN), a federally funded national consortium of representatives from 10 regional genetics networks. Newborn screening programs vary widely in approaches and policies concerning residual dried blood spot samples (DBS) collected for newborn screening. Recognition of the epidemiological utility of DBS samples for HIV seroprevalence surveys and a growing interest in DBSs for DNA analysis has intensified consideration of issues regarding retention, storage, and use of residual DBS samples. Potentially these samples provide a genetic material 'bank' for all newborns nationwide. Their value as a resource for other uses has already been recognized by scientists, administrators, and judicial officials. Programs should promulgate rules for retention and use of residual newborn screening DBS samples based on scientifically valid information. Banking of newborn samples as sources of genetic material should be considered in light of potential benefit or harm to society.

Original languageEnglish (US)
Pages (from-to)116-124
Number of pages9
JournalBiochemical and Molecular Medicine
Volume57
Issue number2
DOIs
StatePublished - 1996
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry

Cite this

Therrell, B. L., Hannon, W. H., Pass, K. A., Lorey, F., Brokopp, C., Eckman, J., Glass, M., Heidenreich, R., Kinney, S., Kling, S., Landenburger, G., Meaney, F. J., Mccabe, E. R. B., Panny, S. R., Schwartz, M., & Shapira, E. (1996). Guidelines for the retention, storage, and use of residual dried blood spot samples after newborn screening analysis: Statement of the council of regional networks for genetic services. Biochemical and Molecular Medicine, 57(2), 116-124. https://doi.org/10.1006/bmme.1996.0017