Guided bone regeneration at the donor site of iliac bone grafts for future use as autogenous grafts

Ahmed Elshahat, Nozumu Inoue, Guy Marti, Ikram Safe, Paul Manson, Craig Vander Kolk

Research output: Contribution to journalArticle

Abstract

Background: Autogenous bone grafting is considered the standard in management of bony defects but has some disadvantages, including limited source of graft material, especially in children. This study represents an attempt to regenerate bone at the donor site of iliac bone grafts using the guided bone regeneration principle for future use in multistage bone reconstruction by grafting. Methods: Critical size defects were created in 24 iliac bones of 12 skeletally mature New Zealand White rabbits. Defects in group 1 (n = 12) were covered with inverted U-shaped resorbable mesh (space maintainer) and polytetrafluoroethylene membranes underneath the periosteum. In group 2 (n = 6), inverted U-shaped resorbable mesh was used alone (positive control). In group 3 (n = 6), neither resorbable mesh nor polytetrafluoroethylene membranes were used (negative control). An unpaired t test was used for comparison between each two groups. Results: Plain radiographs and contact microradiographic studies showed that bone regeneration was significantly higher in group 1 and group 2 than in group 3 (p <0.001). There was no significant difference between group 1 and group 2 regarding density. Conclusions: The periosteum acted as an ideal membrane for guided bone regeneration so that the polytetrafluoroethylene membranes could be used only to compensate for the deficient periosteum. Space maintenance was essential for bone regeneration.

Original languageEnglish (US)
Pages (from-to)1068-1075
Number of pages8
JournalPlastic and Reconstructive Surgery
Volume116
Issue number4
DOIs
StatePublished - Sep 15 2005
Externally publishedYes

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Bone Regeneration
Periosteum
Polytetrafluoroethylene
Tissue Donors
Transplants
Bone and Bones
Membranes
Bone Transplantation
Orthodontic Space Maintenance
Rabbits

ASJC Scopus subject areas

  • Surgery

Cite this

Guided bone regeneration at the donor site of iliac bone grafts for future use as autogenous grafts. / Elshahat, Ahmed; Inoue, Nozumu; Marti, Guy; Safe, Ikram; Manson, Paul; Vander Kolk, Craig.

In: Plastic and Reconstructive Surgery, Vol. 116, No. 4, 15.09.2005, p. 1068-1075.

Research output: Contribution to journalArticle

Elshahat, Ahmed ; Inoue, Nozumu ; Marti, Guy ; Safe, Ikram ; Manson, Paul ; Vander Kolk, Craig. / Guided bone regeneration at the donor site of iliac bone grafts for future use as autogenous grafts. In: Plastic and Reconstructive Surgery. 2005 ; Vol. 116, No. 4. pp. 1068-1075.
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