In this review we have summarized the data regarding the development of the fetal uterine tract in animal models. Morphologically the human fetal uterus has been studied in terms of fusion and recanalization of the Mullerian ducts. We have found that a number of growth factors and their receptors are expressed in the developing fetal uterus. Finally, a cell culture system has been set up that makes it possible to perform in vitro studies regarding the cellular biology of fetal uterine cells. An understanding of Mullerian anomalies can be achieved by further understanding the role of growth factors in normal fetal uterine development.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Reproductive Medicine